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Endocrinology / Hormones

产品 101 到 150 共 236个

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  1. Captopril
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    Captopril

    Catalog No. A11738
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    Captopril是一种血管紧张素转换酶(ACE)抑制剂，用于治疗高血压和某些类型的充血性心力衰竭。 了解更多
  2. Moxonidine
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    Moxonidine

    Catalog No. A11317
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    Moxonidine是新一代中枢作用抗高血压药物。是咪唑啉1型受体（I1-R）选择性激动剂，为降压剂。 了解更多
  3. Fosinopril sodium
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    Fosinopril sodium

    Catalog No. A11748
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    ACE 抑制剂
    Fosinopril sodium是一种血管紧张素转换酶(ACE)抑制剂，用于治疗高血压和某些类型的慢性心力衰竭。 了解更多
  4. Perindopril Erbumine (Aceon)
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    Perindopril Erbumine (Aceon)

    Catalog No. A10710
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    Perindopril Butylamine是一种血管紧张素转化酶（ACE）抑制剂。 了解更多
  5. Lisinopril (Zestril)
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    Lisinopril (Zestril)

    Catalog No. A11876
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    Lisinopril (Zestril)是血管紧张素转换酶抑制剂，用于治疗高血压，充血性心力衰竭和心脏病发作，还用于预防糖尿病的肾和视网膜并发症。 了解更多
  6. Imidapril (Tanatril)
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    Imidapril (Tanatril)

    Catalog No. A11867
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    Imidapril (Tanatril)是血管紧张素转化酶（ACE）的抑制剂。 了解更多
  7. Zofenopril calcium
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    Zofenopril calcium

    Catalog No. A12769
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    ACE 抑制剂
    Zofenopril calcium是一种血管紧张素转化酶ACE抑制剂。 了解更多
  8. Telmisartan
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    Telmisartan

    Catalog No. A10905
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    AT1 拮抗剂
    Telmisartan是一种抑制血管紧张素II AT1受体的血管紧张素II受体拮抗剂。 了解更多
  9. Eprosartan mesylate
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    Eprosartan mesylate

    Catalog No. A13747
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    Eprosartan mesylate是一种竞争性的AT1受体拮抗剂，IC50值为1.4-3.9 nM，消除半衰期为5至7小时。 了解更多
  10. Tasosartan
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    Tasosartan

    Catalog No. A10891
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    Angiotensin II receptor 拮抗剂
    Tasosartan是一种血管紧张素II受体拮抗剂。 了解更多
  11. BIBS39
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    BIBS39

    Catalog No. A14154
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    angiotensin II receptor 拮抗剂
    BIBS39是一种非肽血管紧张素II（AII）受体拮抗剂，可从其特异性结合位点置换[125I] AII，其AII亚型（AT1）受体和K（i）的K（i）值为29+/-7 nM。）AII亚型2（AT2）受体的480+/-110 nM）值。 了解更多
  12. Ramipril
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    Ramipril

    Catalog No. A10778
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    ACE 抑制剂
    Ramipril是一种血管紧张素转化酶（ACE）抑制剂，IC50为5 nM。 了解更多
  13. Azilsartan Medoxomil
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    Azilsartan Medoxomil

    Catalog No. A16420
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    angiotensin II receptor type 1 拮抗剂
    Azilsartan medoxomil是一种口服给药的1型血管紧张素II受体拮抗剂，IC50为0.62 nM。 了解更多
  14. Fimasartan
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    Fimasartan

    Catalog No. A17477
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    non-peptide angiotensin II receptor antagonist
    Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Through oral administration, fimasartan blocks angiotensin II receptor type 1 (AT1 receptors), reducing pro-hypertensive actions of angiotensin II, such as systemic vasoconstriction and water retention by the kidneys. 了解更多
  15. Losartan
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    Losartan

    Catalog No. A17510
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    Angiotensin II receptor antagonist
    Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. 了解更多
  16. H-Val-Pro-Pro-OH
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    H-Val-Pro-Pro-OH

    Catalog No. A18868
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    ACE inhibitor
    H-Val-Pro-Pro-OH, a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. 了解更多
  17. Zofenopril
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    Zofenopril

    Catalog No. A13615
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    ACE inhibitor
    Zofenopril is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 81 μM. 了解更多
  18. SL910102
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    SL910102

    Catalog No. A13591
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    Angiotensin AT1 receptor antagonist
    SL910102 is a nonpeptide angiotensin AT1 receptor antagonist. 了解更多
  19. Valsartan
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    Valsartan

    Catalog No. A10962
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    angiotensin II receptor antagonist
    Valsartan (CGP-48933) is an angiotensin II receptor antagonist for the treatment of high blood pressure and heart failure. 了解更多
  20. Imidaprilate
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    Imidaprilate

    Catalog No. A20003
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    ACE inhibitor
    Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM, and is used in the research of hypertensive disease. 了解更多
  21. Azilsartan medoxomil monopotassium
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    Azilsartan medoxomil monopotassium

    Catalog No. A20860
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    angiotensin II receptor type 1 antagonist
    Azilsartan medoxomil monopotassium is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. 了解更多
  22. Sparsentan
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    Sparsentan

    Catalog No. A20879
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    angiotensin II and endothelin A receptor antagonist
    Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively. 了解更多
  23. Lisinopril
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    Lisinopril

    Catalog No. A21064
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    angiotensin-converting enzyme inhibitor
    Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. 了解更多
  24. CGP-42112
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    CGP-42112

    Catalog No. A21575
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    Angiotensin-II subtype 2 receptor(AT2 R) agonist
    CGP-42112(CGP-42112A) is a potent Angiotensin-II subtype 2 receptor(AT2 R) agonist. 了解更多
  25. Losartan (D4 Carboxylic Acid)
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    Losartan (D4 Carboxylic Acid)

    Catalog No. A21578
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    angiotensin II receptor antagonist
    Losartan D4 Carboxylic Acid is the deuterium labeled Losartan(EXP-3174), which is an angiotensin II receptor antagonist. 了解更多
  26. Azilsartan D5
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    Azilsartan D5

    Catalog No. A21600
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    angiotensin II type 1 receptor antagonist
    Azilsartan D5 is the deuterium labeled Azilsartan(TAK-536), which is a specific and potent angiotensin II type 1 receptor antagonist. 了解更多
  27. AVE 0991
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    AVE 0991

    Catalog No. A20997
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    angiotensin-(1-7) receptor agonist
    AVE 0991 is a nonpeptide and orally active angiotensin-(1-7) receptor agonist with an IC50 of 21 nM. 了解更多
  28. Meclizine 2HCl
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    Meclizine 2HCl

    Catalog No. A11700
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    Meclizine是人类的孕烷X受体（hPXR）激动剂。它具有抗胆碱能，中枢神经系统抑制作用和局部麻醉作用。其止吐和抗眩晕作用尚不完全清楚，但其主要的抗胆碱能特性是部分原因。 了解更多
  29. Pregnenolone
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    Pregnenolone

    Catalog No. A11909
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    Pregnenolone是一种内源性类固醇激素，抑制M1受体和M3受体介导的电流，IC50值分别为11.4μM和6.0μM。 了解更多
  30. Rifampin
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    Rifampin

    Catalog No. A10791
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    RNA polymerase 抑制剂
    Rifampin是DNA依赖性的RNA聚合酶抑制剂，孕烷X受体（PXR）的原型激活剂。 了解更多
  31. SR-12813
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    SR-12813

    Catalog No. A16125
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    PXR 激动剂
    SR-12813是孕烷X受体（PXR）激动剂。 了解更多
  32. β-Sitosterol
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    β-Sitosterol

    Catalog No. A11015
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    5-alpha reductase 抑制剂
    β-Sitosterol是一种植物甾醇，与胆固醇具有相似的化学结构。 了解更多
  33. Dutasteride (Avodart)
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    Dutasteride (Avodart)

    Catalog No. A10338
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    dual 5alpha-reductase 抑制剂
    Dutasteride (Avodart)是双重的5-a还原酶抑制剂，可抑制睾丸激素转化为二氢睾丸激素（DHT）。 了解更多
  34. Finasteride
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    Finasteride

    Catalog No. A10387
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    Finasteride是合成的II型5α-还原酶抑制剂。该酶将睾丸激素转化为二氢睾丸激素(DHT)。 了解更多
  35. Chlormadinone acetate
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    Chlormadinone acetate

    Catalog No. A16443
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    Chlormadinone acetate是一种甾体孕激素，具有额外的抗雄激素和促性腺激素作用，通常与口服避孕药联合使用。 了解更多
  36. Epristeride
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    Epristeride

    Catalog No. A18231
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    5 alpha-reductase inhibitor
    Epristeride is a selective and specific uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. 了解更多
  37. OC 000459
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    OC 000459

    Catalog No. A11946
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    CRTH2 拮抗剂
    OC 000459是一种有效的口服和选择性CRTH2（也称为DP2）拮抗剂。 了解更多
  38. Diphenyleneiodonium chloride
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    Diphenyleneiodonium chloride

    Catalog No. A13359
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    GPR3 激动剂/NOS/ NADPH oxidases 抑制剂
    Diphenyleneiodonium是一种有效的不可逆的巨噬细胞抑制剂NOS2（iNOS）和内皮细胞NOS3（eNOS）抑制剂。 了解更多
  39. MBX-2982
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    MBX-2982

    Catalog No. A12634
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    GPR119 激动剂
    MBX-2982是针对2型糖尿病的潜在一流疗法，其靶向G蛋白偶联受体119（GPR119），该受体与已知刺激葡萄糖依赖性胰岛素分泌的生物活性脂质相互作用。 了解更多
  40. AR-231453
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    AR-231453

    Catalog No. A13716
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    GPR119 激动剂
    AR-231453是GPR119的一种有效的，选择性的小分子药物，可增强葡萄糖依赖性胰岛素分泌和胰高血糖素样肽1（GLP-1）的释放。 了解更多
  41. AZD1981
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    AZD1981

    Catalog No. A13186
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    CRTH2 receptor 拮抗剂
    AZD1981作为疾病相关细胞系统的有效拮抗剂，可抑制DK-PGD2诱导的人嗜酸性粒细胞CD11b表达，IC50为10 nM。 了解更多
  42. APD668
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    APD668

    Catalog No. A14342
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    GPR119 激动剂
    APD668是有效的GPR119激动剂，hGPR119和ratGPR119的EC50分别为2.7 nM和33 nM。 了解更多
  43. AMG 837 calcium hydrate
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    AMG 837 calcium hydrate

    Catalog No. A13468
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    GPR40/FFA1 激动剂
    AMG-837 calcium hydrate是一种口服生物有效的GPR40激动剂。 了解更多
  44. Deoxycholic acid
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    Deoxycholic acid

    Catalog No. A14952
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    Deoxycholic acid是从猪胆汁中提取的，是一种细胞溶解剂。它通过降低细胞膜完整性来发挥其生理作用。 了解更多
  45. GPR120 modulator 1
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    GPR120 modulator 1

    Catalog No. A15094
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    GPR120 modulator 1 可用于调节G蛋白偶联受体120（GPR120）。 了解更多
  46. GPR120 modulator 2
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    GPR120 modulator 2

    Catalog No. A15095
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    GPR120 modulator 2 可用于调节G蛋白偶联受体120（GPR120）。 了解更多
  47. 6-OAU
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    6-OAU

    Catalog No. A15507
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    GPR84 激动剂
    6-OAU是GPR84的替代激动剂；在PI分析中，在HEK293细胞中存在Gqi5嵌合体时，可激活人GPR84，EC50为105 nM。 了解更多
  48. NIBR189
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    NIBR189

    Catalog No. A15775
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    EBI2 (GPR183) receptor 拮抗剂
    NIBR189是爱泼斯坦-巴尔病毒诱导的基因2（EBI2；GPR183）受体的小分子拮抗剂，IC50为16 nM（结合）和11 nM（功能性）。 了解更多
  49. APD597 (JNJ-38431055)
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    APD597 (JNJ-38431055)

    Catalog No. A15452
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    GPR119 激动剂
    APD597 (JNJ-38431055)是一种GPR119激动剂，旨在治疗2型糖尿病，hGPR119的EC50为46 nM。 了解更多
  50. GSK137647A
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    GSK137647A

    Catalog No. A14542
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    FFA4/GPR120 激动剂
    GSK137647A是一种选择性FFA4激动剂，对人，小鼠和大鼠FFA4的pEC50分别为6.3、6.2和6.1。 了解更多

产品 101 到 150 共 236个

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  1. Estrogen Receptors (49)
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  6. Pregnane X Receptors (4)
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