Endocrinology / Hormones
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Epristeride
Catalog No. A18231 5 alpha-reductase inhibitorEpristeride is a selective and specific uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. 了解更多 -
β-Sitosterol
Catalog No. A11015 -
Dutasteride (Avodart)
Catalog No. A10338 dual 5alpha-reductase 抑制剂Dutasteride (Avodart)是双重的5-a还原酶抑制剂,可抑制睾丸激素转化为二氢睾丸激素(DHT)。 了解更多 -
Finasteride
Catalog No. A10387 Finasteride是合成的II型5α-还原酶抑制剂。该酶将睾丸激素转化为二氢睾丸激素(DHT)。 了解更多 -
Chlormadinone acetate
Catalog No. A16443 Chlormadinone acetate是一种甾体孕激素,具有额外的抗雄激素和促性腺激素作用,通常与口服避孕药联合使用。 了解更多 -
Meclizine 2HCl
Catalog No. A11700 Meclizine是人类的孕烷X受体(hPXR)激动剂。它具有抗胆碱能,中枢神经系统抑制作用和局部麻醉作用。其止吐和抗眩晕作用尚不完全清楚,但其主要的抗胆碱能特性是部分原因。 了解更多 -
Pregnenolone
Catalog No. A11909 Pregnenolone是一种内源性类固醇激素,抑制M1受体和M3受体介导的电流,IC50值分别为11.4μM和6.0μM。 了解更多 -
Eprosartan
Catalog No. A11121 -
Olmesartan (RNH6270, CS-088)
Catalog No. A10670 Olmesartan (RNH6270,CS-088)是一种用于治疗高血压的血管紧张素II受体拮抗剂。 了解更多 -
Olmesartan medoxomil
Catalog No. A11615 Olmesartan medoxomil是一种用于治疗高血压的血管紧张素II受体拮抗剂。奥美沙坦通过阻断血管紧张素II与血管肌肉AT1受体的结合来发挥作用。通过阻断结合而不是血管紧张素II的合成,奥美沙坦抑制了对肾素分泌的负面调节反馈。 了解更多 -
Azilsartan (TAK-536)
Catalog No. A11775 -
Fosinopril sodium
Catalog No. A11748 -
Perindopril Erbumine (Aceon)
Catalog No. A10710 Perindopril Butylamine是一种血管紧张素转化酶(ACE)抑制剂。 了解更多 -
Lisinopril (Zestril)
Catalog No. A11876 Lisinopril (Zestril)是血管紧张素转换酶抑制剂,用于治疗高血压,充血性心力衰竭和心脏病发作,还用于预防糖尿病的肾和视网膜并发症。 了解更多 -
Zofenopril calcium
Catalog No. A12769 -
Telmisartan
Catalog No. A10905 -
Eprosartan mesylate
Catalog No. A13747 Eprosartan mesylate是一种竞争性的AT1受体拮抗剂,IC50值为1.4-3.9 nM,消除半衰期为5至7小时。 了解更多 -
Tasosartan
Catalog No. A10891 -
Azilsartan Medoxomil
Catalog No. A16420 angiotensin II receptor type 1 拮抗剂Azilsartan medoxomil是一种口服给药的1型血管紧张素II受体拮抗剂,IC50为0.62 nM。 了解更多 -
Fimasartan
Catalog No. A17477 non-peptide angiotensin II receptor antagonistFimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Through oral administration, fimasartan blocks angiotensin II receptor type 1 (AT1 receptors), reducing pro-hypertensive actions of angiotensin II, such as systemic vasoconstriction and water retention by the kidneys. 了解更多 -
H-Val-Pro-Pro-OH
Catalog No. A18868 ACE inhibitorH-Val-Pro-Pro-OH, a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. 了解更多 -
Zofenopril
Catalog No. A13615 ACE inhibitorZofenopril is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 81 μM. 了解更多 -
Imidaprilate
Catalog No. A20003 ACE inhibitorImidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM, and is used in the research of hypertensive disease. 了解更多 -
Azilsartan medoxomil monopotassium
Catalog No. A20860 angiotensin II receptor type 1 antagonistAzilsartan medoxomil monopotassium is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. 了解更多 -
Sparsentan
Catalog No. A20879 angiotensin II and endothelin A receptor antagonistSparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively. 了解更多 -
Lisinopril
Catalog No. A21064 angiotensin-converting enzyme inhibitorLisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. 了解更多 -
Losartan (D4 Carboxylic Acid)
Catalog No. A21578 angiotensin II receptor antagonistLosartan D4 Carboxylic Acid is the deuterium labeled Losartan(EXP-3174), which is an angiotensin II receptor antagonist. 了解更多 -
Azilsartan D5
Catalog No. A21600 angiotensin II type 1 receptor antagonistAzilsartan D5 is the deuterium labeled Azilsartan(TAK-536), which is a specific and potent angiotensin II type 1 receptor antagonist. 了解更多 -
Aliskiren hemifumarate
Catalog No. A11123 -
Candesartan (Atacand)
Catalog No. A10175 RAAS 拮抗剂Candesartan (Atacand)是一种血管紧张素受体阻滞剂(也称为血管紧张素II受体拮抗剂或AIIRA)。 了解更多 -
Benazepril HCl
Catalog No. A10123 -
Clinofibrate
Catalog No. A11184 HMG-CoA Reductase 抑制剂Clinofibrate是一种脂质清除剂,似乎可以改变脂质代谢,减少类固醇诱导的骨细胞内脂质堆积。它还可以有效降低血浆纤维蛋白原水平。抑制hydroxymethylglutaryl coenzyme A reductase (HMGCR)(羟甲基戊二酰辅酶A还原酶),IC50为0.47 mM。 了解更多 -
Rosuvastatin
Catalog No. A11122 -
Irbesartan (Avapro)
Catalog No. A10477 -
Aliskiren (CGP 60536)
Catalog No. A11616 -
Candesartan cilexetil (Atacand)
Catalog No. A10176 Candesartan Cilexetil一种特异性的,非肽类血管生成素II受体(ATR)拮抗剂,也是Candesartan的前体药物,是ATR拮抗剂 了解更多 -
Quinapril hydrochloride
Catalog No. A11736 Quinapril hydrochloride是一种催化血管紧张素II从其前体血管紧张素I形成的酶。 了解更多 -
Moexipril hydrochloride
Catalog No. A11745 Moexipril hydrochloride是一种有效的口服活性非巯基血管紧张素转换酶抑制剂(ACE),可作用于高血压和充血性心力衰竭。 了解更多