Endoxifen

目录号: A12639

Estrogen receptor 拮抗剂

Endoxifen

Endoxifen Chemical Structure

CAS NO. 112093-28-4

Endoxifen是他莫昔芬的次生代谢产物。它是负责他莫昔芬在ER阳性乳腺癌中有效性的主要代谢物。Endoxifen Z-isomer抑制hERG, 这种作用具有浓度依赖性, IC50值为1.6μM。

库存: 现货

规格 价格 数量
10 mg
¥ 490.00
25 mg
¥ 980.00
50 mg
¥ 1,540.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Endoxifen是他莫昔芬的次生代谢产物。它是负责他莫昔芬在ER阳性乳腺癌中有效性的主要代谢物。Endoxifen Z-isomer抑制hERG, 这种作用具有浓度依赖性, IC50值为1.6μM。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.77 mL 133.87 mL 267.74 mL
0.5 mM 5.35 mL 26.77 mL 53.55 mL
1 mM 2.68 mL 13.39 mL 26.77 mL
5 mM 0.54 mL 2.68 mL 5.35 mL

*The above data is based on the productmolecular weight 373.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12639
作用机制 Antagonist (拮抗剂)
M. Wt 373.49
Formula C25H27NO2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 112093-28-4
SMILES CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCNC)C3=CC=CC=C3

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