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Entecavir hydrate，一个新的脱氧鸟嘌呤核苷类似物，是乙肝病毒复制的选择性抑制剂。
靶点信息
| Reverse Transcriptase | ||||
| In vitro | DMSO | 52 mg/mL (176.09 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.86 mL | 169.32 mL | 338.64 mL |
| 0.5 mM | 6.77 mL | 33.86 mL | 67.73 mL |
| 1 mM | 3.39 mL | 16.93 mL | 33.86 mL |
| 5 mM | 0.68 mL | 3.39 mL | 6.77 mL |
*The above data is based on the productmolecular weight 295.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11216 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 295.3 |
| Formula | C12H15N5O3.H2O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 209216-23-9, 142217-69-4 |
| Synonyms | ETV, Baraclude |
| SMILES | C=C1[C@@H]([C@H](CC1N2C=NC3=C2NC(=NC3=O)N)O)CO.O |
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