微信关注
China
Total item
Cart Subtotal
￥ 0.00 Epigenetics
-
TCS 401 free base
Catalog No. A15390 PTP1B 抑制剂TCS 401是蛋白酪氨酸磷酸酶1B（PTP1B）的选择性抑制剂（对于PTP1B，CD45 D1D2，PTPβ，PTPεD1，SHP-1，Ki值为0.29、59、560、1100，> 2000，> 2000和> 2000μM，分别为PTPαD1和LAR D1D2）。 了解更多 -
DPM-1001
Catalog No. A18674 PTP1B inhibitorDPM-1001 is a potent, specific, orally bioavailable and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC50 of 100 nM, an an analog of the specific PTP1B inhibitor trodusquemine (MSI-1436; IC50=600 nM). DPM-1001 has anti-diabetic property. 了解更多 -
PTP1B-IN-8
Catalog No. A19109 PTP1B inhibitorPTP1B-IN-8 is a potent and selective potent protein tyrosine phosphatase-1B (PTP1B) inhibitor extracted from patent CN103626692A, example 1. 了解更多 -
PTP1B-IN-3
Catalog No. A21149 PTP1B inhibitorPTP1B-IN-3 is a potent and selective PTP1B inhibitor with IC50s of 120 nM (PTP1B) and 120 nM (TCPTP), respectively. 了解更多 -
PTP1B-IN-1
Catalog No. A22000 PTP1B inhibitorPTP1B-IN-1 is a potent protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 1.6 mM; 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for derivatives synthesis. 了解更多 -
FK-506 (Tacrolimus)
Catalog No. A10389 mTOR 抑制剂FK-506 (Tacrolimus)是一种免疫抑制药物，通过结合到抑免蛋白FKBP12 (FK506 结合蛋白)产生新的复合物，从而降低T细胞中肽酰脯氨酰异构酶活性。 了解更多 -
Ascomycin
Catalog No. A12592 -
INCA-6
Catalog No. A15380 -
Ascomycin (FK520)
Catalog No. A15788 Calcineurin/PP2B 抑制剂Ascomycin (FK520)是他克莫司的乙基类似物（FK506），具有强的免疫抑制特性。已经研究出其用于治疗自身免疫疾病和皮肤疾病，并防止器官移植后的排斥反应。 了解更多 -
Cyclosporine
Catalog No. A15434 -
C7280948
Catalog No. A13876 -
MS023
Catalog No. A12585 -
HLCL-61
Catalog No. A15870 -
GSK-3326595 (EPZ015938)
Catalog No. A16862 PRMT5 抑制剂GSK-3326595 (EPZ015938)是一种有效的，选择性的，可逆的蛋白精氨酸甲基转移酶5（PRMT5）抑制剂，IC50为6.2 nM。 了解更多 -
PF-06855800
Catalog No. A16860 PRMT5 抑制剂PF-06855800 (PF06855800)是一种有效的，选择性的，SAM竞争性，BBB渗透性，口服活性的蛋白精氨酸甲基转移酶PRMT5抑制剂，Ki为0.02 nM。 了解更多 -
BIX 01294
Catalog No. A11763 -
EPZ-5676 (Pinometostat)
Catalog No. A12735 DOT1L 抑制剂?EPZ-5676 (Pinometostat)是组蛋白甲基转移酶的小分子抑制剂，具有潜在的抗肿瘤活性。 了解更多 -
UNC0631
Catalog No. A13195 -
Opicapone (BIA 9-1067)
Catalog No. A13110 -
UNC0321
Catalog No. A13200 -
EPZ-6438 (Tazemetostat)
Catalog No. A12712 EZH2 抑制剂EPZ-6438 (Tazemetostat)是一种有效的，选择性的，口服可利用的EZH2酶促活性小分子抑制剂，无细胞试验中Ki 和 IC50分别为2.5 nM 和 11 nM。它诱导SMARCB1缺失的MRT细胞中的凋亡和分化。 了解更多 -
EPZ004777
Catalog No. A12983 -
SGC 0946
Catalog No. A12941 -
UNC 0638
Catalog No. A13690 -
MI-3
Catalog No. A14218 -
3-deazaneplanocin A HCl (DZNep HCl)
Catalog No. A13947 EZH2 抑制剂3-deazaneplanocin A，也称为DZNep，是众所周知的组蛋白甲基转移酶抑制剂，可破坏包括急性髓样白血病，乳腺癌在内的癌细胞中的多梳抑制复合物2（PRC2），并诱导细胞凋亡，同时抑制增殖和转移。癌症和胶质母细胞瘤。 了解更多 -
UNC 0224
Catalog No. A15388 -
MI-2 (Menin-MLL inhibitor 2)
Catalog No. A12929 Menin-MLL interaction 抑制剂MI-2 (Menin-MLL inhibitor 2)特异性结合menin并抑制menin与细胞中mll融合蛋白的相互作用。它能有效逆转mll融合蛋白通过下调mll融合蛋白致癌活性下游靶基因的表达来介导白血病转化。mi-2是更好地理解mll介导的白血病发生的新工具，代表了研究menin作为mll融合蛋白致癌辅助因子的作用的新方法。 了解更多
FILTER BY:
Filtering:
- 作用机制: Inhibitor (抑制剂) 删除该内容
购物选项
- 分类
-
- HDAC (88)
- PARP (44)
- JAK (79)
- Pim (15)
- Aurora Kinase (35)
- Sirtuins (14)
- Epigenetic Reader Domain (70)
- Histone Demethylases (28)
- DNA Methyltransferases (13)
- Histone Acetyltransferases (18)
- Histone Methyltransferase (59)
- Protein Arginine Methyltransferases (12)
- Protein serine/threonine phosphatase (5)
- Protein Tyrosine Phosphatase (9)
- 靶点
-
- 2OG oxygenases (2)
- A3 adenosine receptor (1)
- Abl (3)
- Aurora A (27)
- Aurora B (22)
- Aurora C (11)
- BAZ2A (2)
- BAZ2B (2)
- Bcr-Abl (1)
- BET (5)
- BRD2 (7)
- BRD3 (4)
- BRD4 (9)
- BRD7 (1)
- BRD9 (4)
- BRPF1 (4)
- BRPF2 (1)
- CDK (3)
- CDK4 (1)
- CECR2 (1)
- COMT (1)
- CYP3A4 (1)
- DNMT (6)
- DNMT1 (1)
- DNMT3A (1)
- DNMT3B (2)
- DOT1L (3)
- EGFR (3)
- ErbB2 (1)
- EZH1 (1)
- EZH2 (14)
- FAK (1)
- FGFR1 (3)
- FGFR2 (1)
- FGFR3 (1)
- FLT3 (9)
- G9a (EHMT2) (10)
- GLP (EHMT1) (5)
- HAT (1)
- HD1 (2)
- HD2 (1)
- HDAC (20)
- HDAC1 (24)
- HDAC10 (4)
- HDAC11 (4)
- HDAC2 (15)
- HDAC3 (19)
- HDAC4 (6)
- HDAC5 (4)
- HDAC6 (23)
- HDAC7 (2)
- HDAC8 (9)
- HDAC9 (3)
- HER2 (1)
- IGF1R (1)
- JAK1 (18)
- JAK2 (38)
- JAK3 (17)
- Jumonji histone demethylase (1)
- KAT5 (Tip60) (3)
- KDM1A (LSD1) (8)
- KDM2 (1)
- KDM4 (JMJD2) (1)
- KDM5 (JARID1) (4)
- KDM6A (UTX) (2)
- KDM6B (JMJD3) (2)
- KDM7 (1)
- L3MBTL (2)
- L3MBTL1 (1)
- Lck (1)
- MAO-A (1)
- MAO-B (1)
- Mdm2 (1)
- MEK1 (2)
- MEK2 (1)
- Menin-MLL interaction (2)
- MGMT (2)
- MLL1 (1)
- Mnk1 (1)
- Mnk2 (1)
- NAT10 (1)
- NF-κB (1)
- p110α (1)
- p110β (1)
- p110γ (1)
- p110δ (1)
- p300/CBP (7)
- p53 (1)
- PARP (13)
- PARP1 (10)
- PARP2 (4)
- PCAF (1)
- PDE3 (1)
- PDE5 (1)
- Pim1 (9)
- Pim2 (7)
- Pim3 (5)
- PKCα (1)
- PKCβ (1)
- PRMT1 (4)
- PRMT3 (2)
- PRMT5 (2)
- PRMT6 (1)
- RET (2)
- SETD7 (1)
- SETD8 (1)
- SIRT1 (3)
- SIRT2 (5)
- SMYD2 (2)
- SMYD3 (2)
- Src (3)
- STAT1 (1)
- STAT3 (3)
- STAT5 (1)
- SUV39H (1)
- Syk (2)
- TAF1 (1)
- Tankyrase-1 (5)
- Tankyrase-2 (8)
- TrkA (2)
- Tyk2 (5)
- VEGFR2 (FLK1) (1)
联系我们
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
Not your Region? View all Distributors
ADOOQ 产品质量保证
We promise all products to perform as described.