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￥ 0.00 Epigenetics
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MG149
Catalog No. A14267 -
YF-2
Catalog No. A21018 histone acetyltransferase activatorYF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease. 了解更多 -
CPI-360
Catalog No. A15908 -
Flopropione
Catalog No. A16550 5-HT1A receptor antagonist/COMT inhibitorFlopropione是5-HT1A受体拮抗剂，也是儿茶酚-邻甲基转移酶（COMT）抑制剂。 了解更多 -
SMYD3-IN-1
Catalog No. A18572 SMYD3 inhibitorSMYD3-IN-1 (compound 29) is an irreversible and selective inhibitor of SMYD3 (SET and MYND domain containing 3), with an IC50 of 11.7 nM. 了解更多 -
Entacapone
Catalog No. A10355 COMT inhibitorEntacapone is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment. 了解更多 -
CPUY074020
Catalog No. A12190 G9a inhibitorCPUY074020 is a potent G9a inhibitor with an IC50 of 2.18 μM, and possesses anti-proliferative activity . 了解更多 -
PF-06821497
Catalog No. A21388 EZH2 inhibitorPF-06821497 (compound 23a) is a potent, selective and orally active Enhancer of Zeste Homolog 2 (EZH2) inhibitor, with a Ki value <0.1 nM against mutant Y641N EZH2. Exhibits robust tumor growth inhibition. 了解更多 -
GSK2807 Trifluoroacetate
Catalog No. A21731 SMYD3 inhibitorGSK2807 Trifluoroacetate is a potent, selective and SAM-competitive inhibitor of SMYD3, with a Ki of 14 nM and an IC50 of 130 nM. 了解更多 -
Tazemetostat hydrobromide
Catalog No. A21759 EZH2 inhibitorTazemetostat hydrobromide (EPZ-6438 hydrobromide) is a potent, selective and orally available EZH2 inhibitor. 了解更多 -
Entacapone sodium salt
Catalog No. A21888 COMT inhibitorEntacapone is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment. 了解更多 -
MM-589 TFA
Catalog No. A21892 WDR5 and MLL protein-protein interaction inhibitorMM-589 TFA is a potent inhibitor of WD repeat domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interaction. 了解更多 -
MM-102 TFA
Catalog No. A21941 WDR5/MLL interaction inhibitorMM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM with an estimated Ki < 1 nM in WDR5 binding assay, which is >200 times more potent than the ARA peptide. 了解更多 -
BIX 01294
Catalog No. A11763 -
EPZ-5676 (Pinometostat)
Catalog No. A12735 DOT1L 抑制剂?EPZ-5676 (Pinometostat)是组蛋白甲基转移酶的小分子抑制剂，具有潜在的抗肿瘤活性。 了解更多 -
UNC0631
Catalog No. A13195 -
Opicapone (BIA 9-1067)
Catalog No. A13110 -
UNC0321
Catalog No. A13200 -
EPZ-6438 (Tazemetostat)
Catalog No. A12712 EZH2 抑制剂EPZ-6438 (Tazemetostat)是一种有效的，选择性的，口服可利用的EZH2酶促活性小分子抑制剂，无细胞试验中Ki 和 IC50分别为2.5 nM 和 11 nM。它诱导SMARCB1缺失的MRT细胞中的凋亡和分化。 了解更多 -
EPZ004777
Catalog No. A12983 -
SGC 0946
Catalog No. A12941 -
UNC 0638
Catalog No. A13690 -
MI-3
Catalog No. A14218 -
3-deazaneplanocin A HCl (DZNep HCl)
Catalog No. A13947 EZH2 抑制剂3-deazaneplanocin A，也称为DZNep，是众所周知的组蛋白甲基转移酶抑制剂，可破坏包括急性髓样白血病，乳腺癌在内的癌细胞中的多梳抑制复合物2（PRC2），并诱导细胞凋亡，同时抑制增殖和转移。癌症和胶质母细胞瘤。 了解更多 -
UNC 0224
Catalog No. A15388 -
MI-2 (Menin-MLL inhibitor 2)
Catalog No. A12929 Menin-MLL interaction 抑制剂MI-2 (Menin-MLL inhibitor 2)特异性结合menin并抑制menin与细胞中mll融合蛋白的相互作用。它能有效逆转mll融合蛋白通过下调mll融合蛋白致癌活性下游靶基因的表达来介导白血病转化。mi-2是更好地理解mll介导的白血病发生的新工具，代表了研究menin作为mll融合蛋白致癌辅助因子的作用的新方法。 了解更多 -
A-366
Catalog No. A15969
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