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TCS 401 free base
Catalog No. A15390 PTP1B 抑制剂TCS 401是蛋白酪氨酸磷酸酶1B（PTP1B）的选择性抑制剂（对于PTP1B，CD45 D1D2，PTPβ，PTPεD1，SHP-1，Ki值为0.29、59、560、1100，> 2000，> 2000和> 2000μM，分别为PTPαD1和LAR D1D2）。 了解更多 -
DPM-1001
Catalog No. A18674 PTP1B inhibitorDPM-1001 is a potent, specific, orally bioavailable and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC50 of 100 nM, an an analog of the specific PTP1B inhibitor trodusquemine (MSI-1436; IC50=600 nM). DPM-1001 has anti-diabetic property. 了解更多 -
PTP1B-IN-8
Catalog No. A19109 PTP1B inhibitorPTP1B-IN-8 is a potent and selective potent protein tyrosine phosphatase-1B (PTP1B) inhibitor extracted from patent CN103626692A, example 1. 了解更多 -
PTP1B-IN-3
Catalog No. A21149 PTP1B inhibitorPTP1B-IN-3 is a potent and selective PTP1B inhibitor with IC50s of 120 nM (PTP1B) and 120 nM (TCPTP), respectively. 了解更多 -
PTP1B-IN-1
Catalog No. A22000 PTP1B inhibitorPTP1B-IN-1 is a potent protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 1.6 mM; 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for derivatives synthesis. 了解更多 -
FK-506 (Tacrolimus)
Catalog No. A10389 mTOR 抑制剂FK-506 (Tacrolimus)是一种免疫抑制药物，通过结合到抑免蛋白FKBP12 (FK506 结合蛋白)产生新的复合物，从而降低T细胞中肽酰脯氨酰异构酶活性。 了解更多 -
Ascomycin
Catalog No. A12592 -
Calcineurin Autoinhibitory Peptide
Catalog No. A15376 Calcineurin Autoinhibitory Peptide是Ca2+钙调蛋白依赖性蛋白磷酸酶（钙调神经磷酸酶）（IC50?10 uM）的选择性抑制剂。不抑制PP1，PP2A或CaM激酶II（IC50> 100 mM）。 了解更多 -
INCA-6
Catalog No. A15380 -
Ascomycin (FK520)
Catalog No. A15788 Calcineurin/PP2B 抑制剂Ascomycin (FK520)是他克莫司的乙基类似物（FK506），具有强的免疫抑制特性。已经研究出其用于治疗自身免疫疾病和皮肤疾病，并防止器官移植后的排斥反应。 了解更多 -
Cyclosporine
Catalog No. A15434 -
C7280948
Catalog No. A13876 -
MS023
Catalog No. A12585 -
HLCL-61
Catalog No. A15870 -
GSK-3326595 (EPZ015938)
Catalog No. A16862 PRMT5 抑制剂GSK-3326595 (EPZ015938)是一种有效的，选择性的，可逆的蛋白精氨酸甲基转移酶5（PRMT5）抑制剂，IC50为6.2 nM。 了解更多 -
PF-06855800
Catalog No. A16860 PRMT5 抑制剂PF-06855800 (PF06855800)是一种有效的，选择性的，SAM竞争性，BBB渗透性，口服活性的蛋白精氨酸甲基转移酶PRMT5抑制剂，Ki为0.02 nM。 了解更多 -
Amodiaquine dihydrochloride dihydrate
Catalog No. A16405 Amodiaquine dihydrochloride dihydrate是人红细胞中组胺N-甲基转移酶的有效，非竞争性抑制剂，也用作抗疟疾和抗炎药。 了解更多 -
BIX 01294
Catalog No. A11763 -
EPZ-5676 (Pinometostat)
Catalog No. A12735 DOT1L 抑制剂?EPZ-5676 (Pinometostat)是组蛋白甲基转移酶的小分子抑制剂，具有潜在的抗肿瘤活性。 了解更多 -
UNC0631
Catalog No. A13195 -
Opicapone (BIA 9-1067)
Catalog No. A13110 -
UNC0321
Catalog No. A13200 -
EPZ-6438 (Tazemetostat)
Catalog No. A12712 EZH2 抑制剂EPZ-6438 (Tazemetostat)是一种有效的，选择性的，口服可利用的EZH2酶促活性小分子抑制剂，无细胞试验中Ki 和 IC50分别为2.5 nM 和 11 nM。它诱导SMARCB1缺失的MRT细胞中的凋亡和分化。 了解更多 -
EPZ004777
Catalog No. A12983 -
SGC 0946
Catalog No. A12941 -
UNC 0638
Catalog No. A13690 -
MI-3
Catalog No. A14218 -
3-deazaneplanocin A HCl (DZNep HCl)
Catalog No. A13947 EZH2 抑制剂3-deazaneplanocin A，也称为DZNep，是众所周知的组蛋白甲基转移酶抑制剂，可破坏包括急性髓样白血病，乳腺癌在内的癌细胞中的多梳抑制复合物2（PRC2），并诱导细胞凋亡，同时抑制增殖和转移。癌症和胶质母细胞瘤。 了解更多 -
UNC 0224
Catalog No. A15388
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