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ETP-46321是一种有效且口服可生物利用的PI3Kα/δ抑制剂，口服后具有有效的生化和细胞活性，并具有良好的药代动力学特性（PK）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.12 mL | 105.59 mL | 211.17 mL |
| 0.5 mM | 4.22 mL | 21.12 mL | 42.23 mL |
| 1 mM | 2.11 mL | 10.56 mL | 21.12 mL |
| 5 mM | 0.42 mL | 2.11 mL | 4.22 mL |
*The above data is based on the productmolecular weight 473.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16271 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 473.55 |
| Formula | C20H27N9O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1252594-99-2 |
| Synonyms | ETP46321, ETP 46321 |
| SMILES | NC1=NC=C(C2=CN3C(C(N4CCOCC4)=N2)=NC(CN5CCN(S(=O)(C)=O)CC5)=C3)C=N1 |
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