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Evista (Raloxifene HCl)是一种口服选择性雌激素受体调节剂（SERM），对骨骼具有雌激素作用，对子宫和乳房具有抗雌激素作用。
靶点信息
| ER | ||||
| 5.7 nM |
| In vitro (25°C) | DMSO | 90 mg/mL (176.45 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 1% methylcellulose | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.61 mL | 98.04 mL | 196.08 mL |
| 0.5 mM | 3.92 mL | 19.61 mL | 39.22 mL |
| 1 mM | 1.96 mL | 9.8 mL | 19.61 mL |
| 5 mM | 0.39 mL | 1.96 mL | 3.92 mL |
*The above data is based on the productmolecular weight 510. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10375 |
|---|---|
| M. Wt | 510 |
| Formula | C28H28ClNO4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 82640-04-8 |
| SMILES | C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl |
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