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EX 527 (Selisistat)

EX 527 (Selisistat)

Name: EX 527 (Selisistat)
SKU: A10377

目录号: A10377

SIRT1 抑制剂

Product Citations (5)

EX 527 (Selisistat) Chemical Structure

CAS NO. 49843-98-3

EX 527 (Selisistat)是一种有效的选择性SIRT1 III类组蛋白脱乙酰基酶抑制剂，在无细胞分析中的IC50为38 nM。

库存：现货

规格	价格	数量
5 mg	￥ 175.00
10 mg	￥ 280.00
25 mg	￥ 490.00
100 mg	￥ 1,400.00
10mM * 1mL in DMSO	￥ 497.00

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生物活性

EX 527 (Selisistat)是一种有效的选择性SIRT1 III类组蛋白脱乙酰基酶抑制剂，在无细胞分析中的IC50为38 nM。

靶点信息

SIRT1 (Cell-free assay)
38 nM

溶解度 *

In vitro (25°C)	DMSO	46 mg/mL (184.95 mM)
	Water	Insoluble
	Ethanol	17 mg/mL (68.35 mM)
In vivo	5% DMSO+30% PEG 300+ddH2O	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	40.21 mL	201.05 mL	402.09 mL
0.5 mM	8.04 mL	40.21 mL	80.42 mL
1 mM	4.02 mL	20.1 mL	40.21 mL
5 mM	0.8 mL	4.02 mL	8.04 mL

*The above data is based on the productmolecular weight 248.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10377
作用机制	Inhibitor (抑制剂)
M. Wt	248.7
Formula	C13H13ClN2O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	49843-98-3
Synonyms	EX527, EX-527
SMILES	C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N