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EXP-3174是一种有效的选择性非竞争性AT1受体拮抗剂,IC50值为37 nM。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.89 mL | 114.45 mL | 228.89 mL |
0.5 mM | 4.58 mL | 22.89 mL | 45.78 mL |
1 mM | 2.29 mL | 11.44 mL | 22.89 mL |
5 mM | 0.46 mL | 2.29 mL | 4.58 mL |
*The above data is based on the productmolecular weight 436.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A15451 |
---|---|
作用机制 | Antagonist (拮抗剂) |
M. Wt | 436.89 |
Formula | C22H21ClN6O2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 124750-92-1 |
Synonyms | Losartan Carboxylic Acid, EXP 3174, EXP3174 |
SMILES | CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)Cl |
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