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FMF-04-159-2 is a covalent CDK14 inhibitor. FMF-04-159-2 inhibits CDK14 and CDK2 with IC50s of 39.6 nM and 256 nM in NanoBRET assay, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.64 mL | 73.21 mL | 146.41 mL |
| 0.5 mM | 2.93 mL | 14.64 mL | 29.28 mL |
| 1 mM | 1.46 mL | 7.32 mL | 14.64 mL |
| 5 mM | 0.29 mL | 1.46 mL | 2.93 mL |
*The above data is based on the productmolecular weight 683. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18911 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 683 |
| Formula | C28H30Cl3N7O5S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2364489-81-4 |
| Synonyms | FMF-04-159-2; FMF041592; FMF 04 159 2; |
| SMILES | O=C(C1=NNC=C1NC(C2=C(Cl)C=C(Cl)C=C2Cl)=O)NC3CCN(S(=O)(C4=CC=CC(NC(/C=C/CN(C)C)=O)=C4)=O)CC3 |
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