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Furosemide是GABAA受体的非竞争性拮抗剂，对含α6受体的选择性比含α1受体高约100倍。
靶点信息
| NKCC2 | ||||
| In vitro | DMSO | 63 mg/mL (190.48 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.24 mL | 151.18 mL | 302.35 mL |
| 0.5 mM | 6.05 mL | 30.24 mL | 60.47 mL |
| 1 mM | 3.02 mL | 15.12 mL | 30.24 mL |
| 5 mM | 0.6 mL | 3.02 mL | 6.05 mL |
*The above data is based on the productmolecular weight 330.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10412 |
|---|---|
| M. Wt | 330.74 |
| Formula | C12H11ClN2O5S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 54-31-9 |
| Synonyms | Lasix |
| SMILES | C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)O)S(=O)(=O)N)Cl |
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