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G-479是有效的MEK抑制剂。在许多方面，极性分布在整个分子中的G-479被证明具有比GDC-0623更高的生物活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.52 mL | 102.62 mL | 205.25 mL |
| 0.5 mM | 4.1 mL | 20.52 mL | 41.05 mL |
| 1 mM | 2.05 mL | 10.26 mL | 20.52 mL |
| 5 mM | 0.41 mL | 2.05 mL | 4.1 mL |
*The above data is based on the productmolecular weight 487.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14380 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 487.22 |
| Formula | C16H15FIN5O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1168092-22-5 |
| Synonyms | G479, G 479 |
| SMILES | O=C(C1=C(NC2=CC=C(I)C=C2F)N3C(C=N1)=CN=C3)NOC[C@H](O)CO |
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