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GS-7340是替诺福韦（TFV）的前药，它比TFV富马酸二甲酚更有效地将TFV输送到淋巴样细胞和组织中。
靶点信息
| Reverse transcriptase | ||||
| In vitro | DMSO | 94 mg/mL (197.28 mM) | |
| Water | Insoluble | ||
| Ethanol | 94 mg/mL (197.28 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.99 mL | 104.94 mL | 209.88 mL |
| 0.5 mM | 4.2 mL | 20.99 mL | 41.98 mL |
| 1 mM | 2.1 mL | 10.49 mL | 20.99 mL |
| 5 mM | 0.42 mL | 2.1 mL | 4.2 mL |
*The above data is based on the productmolecular weight 476.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15772 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 476.47 |
| Formula | C21H29N6O5P |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 379270-37-8 |
| Synonyms | GS7340, GS 7340, Tenofovir alafenamide |
| SMILES | CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C1N=CN=C2N)OC3=CC=CC=C3 |
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