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GS967是一种新型的，有效的，选择性的心脏晚期钠电流抑制剂（INa晚期）；抑制心室肌细胞和离体心脏中ATX-II诱导的晚期I（Na），IC（50）值分别为0.13和0.21 uM。
| In vitro | DMSO | 38 mg/mL (109.44 mM) | |
| Water | Insoluble | ||
| Ethanol | 39 mg/mL (112.32 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.8 mL | 144 mL | 288 mL |
| 0.5 mM | 5.76 mL | 28.8 mL | 57.6 mL |
| 1 mM | 2.88 mL | 14.4 mL | 28.8 mL |
| 5 mM | 0.58 mL | 2.88 mL | 5.76 mL |
*The above data is based on the productmolecular weight 347.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14361 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 347.22 |
| Formula | C14H7F6N3O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1262618-39-2 |
| Synonyms | GS-967, GS 967 |
| SMILES | FC(F)(F)C1=NN=C2C=CC(C3=CC=C(OC(F)(F)F)C=C3)=CN21 |
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