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GSK1278863 (Daprodustat)

GSK1278863 (Daprodustat)

Name: GSK1278863 (Daprodustat)
SKU: A12671

目录号: A12671

HIF-prolyl hydroxylase 抑制剂

GSK1278863 (Daprodustat) Chemical Structure

CAS NO. 960539-70-2

GSK1278863是新型的HIF-脯氨酰羟化酶抑制剂。

库存：现货

规格	价格	数量
5 mg	￥ 504.00
10 mg	￥ 854.00
25 mg	￥ 1,512.00

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产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

GSK1278863是新型的HIF-脯氨酰羟化酶抑制剂。

靶点信息

HIF-PH

溶解度 *

In vitro	DMSO	Warmed: 9 mg/mL (22.87 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.42 mL	127.08 mL	254.17 mL
0.5 mM	5.08 mL	25.42 mL	50.83 mL
1 mM	2.54 mL	12.71 mL	25.42 mL
5 mM	0.51 mL	2.54 mL	5.08 mL

*The above data is based on the productmolecular weight 393.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12671
作用机制	Inhibitor (抑制剂)
M. Wt	393.44
Formula	C19H27N3O6
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	960539-70-2
Synonyms	Daprodustat, GSK 1278863, GSK-1278863
SMILES	O=C(O)CNC(C(C(N1C2CCCCC2)=O)C(N(C3CCCCC3)C1=O)=O)=O