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GSK2636771是一种有效的口服生物可用的PI3Kβ选择性抑制剂。
靶点信息
| PI3Kβ | ||||
| In vitro | DMSO | 28 mg/mL (64.6 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.07 mL | 115.37 mL | 230.73 mL |
| 0.5 mM | 4.61 mL | 23.07 mL | 46.15 mL |
| 1 mM | 2.31 mL | 11.54 mL | 23.07 mL |
| 5 mM | 0.46 mL | 2.31 mL | 4.61 mL |
*The above data is based on the productmolecular weight 433.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11784 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 433.4 |
| Formula | C22H22F3N3O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1372540-25-4 |
| Synonyms | GSK 2636771 |
| SMILES | CC1=C(C=CC=C1C(F)(F)F)CN2C(=NC3=C2C=C(C=C3C(=O)O)N4CCOCC4)C |
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