产品详情
Guanabenz acetate是a2A-AR肾上腺素能激动剂和IGRS(咪唑啉I2结合位点)选择性配体。
靶点信息
α2a-adrenergic receptor | α2b-adrenergic receptor | α2c-adrenergic receptor | ||
8.25(pEC50) | 7.01(pEC50) | <5(pEC50) |
In vitro (25°C) | DMSO | 56 mg/mL (192.35 mM) | |
Water | Insoluble | ||
Ethanol | 5 mg/mL (17.17 mM) | ||
In vivo | 4% DMSO+30% PEG 300+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 34.35 mL | 171.74 mL | 343.49 mL |
0.5 mM | 6.87 mL | 34.35 mL | 68.7 mL |
1 mM | 3.43 mL | 17.17 mL | 34.35 mL |
5 mM | 0.69 mL | 3.43 mL | 6.87 mL |
*The above data is based on the productmolecular weight 291.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13635 |
---|---|
作用机制 | Agonist (激动剂) |
M. Wt | 291.13 |
Formula | C10H12Cl2N4O2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 23256-50-0 |
SMILES | CC(=O)O.C1=CC(=C(C(=C1)Cl)/C=N/N=C(N)N)Cl |
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