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GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.87 mL | 89.34 mL | 178.69 mL |
| 0.5 mM | 3.57 mL | 17.87 mL | 35.74 mL |
| 1 mM | 1.79 mL | 8.93 mL | 17.87 mL |
| 5 mM | 0.36 mL | 1.79 mL | 3.57 mL |
*The above data is based on the productmolecular weight 559.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18343 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 559.64 |
| Formula | C31H39F2NO6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 827319-43-7 |
| Synonyms | GW 870086 , GW870086 |
| SMILES | C[C@@]12[C@](C(OCC#N)=O)(OC(C3C(C)(C)C3(C)C)=O)[C@H](C)C[C@@]1([H])[C@]4([H])C[C@H](F)C5=CC(C=C[C@]5(C)[C@@]4(F)[C@@H](O)C2)=O |
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