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GYKI-52466 dihydrochloride是选择性非竞争性AMPA受体拮抗剂(对于AMPA、红藻氨酸和AMPA诱导的反应，IC50值分别为10-20、~ 450和> > 50 μM)。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.3 mL | 136.52 mL | 273.04 mL |
| 0.5 mM | 5.46 mL | 27.3 mL | 54.61 mL |
| 1 mM | 2.73 mL | 13.65 mL | 27.3 mL |
| 5 mM | 0.55 mL | 2.73 mL | 5.46 mL |
*The above data is based on the productmolecular weight 366.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10444 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 366.24 |
| Formula | C17H15N3O2.2HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 102771-26-6 |
| Synonyms | GYKI52466, GYKI 52466 |
| SMILES | CC1=NN=C(C2=CC3=C(C=C2C1)OCO3)C4=CC=C(C=C4)N |
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