Hedgehog

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  1. U18666A

    Catalog No. A20195
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    cholesterol synthesis/Hedgehog inhibitor
    U18666A, a cell permeable drug, is a cholesterol synthesis and transport inhibitor. 了解更多
  2. Mebendazole

    Catalog No. A16606
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    Hedgehog inhibitor
    Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations; has been found as a hedgehog inhibitor. 了解更多
  3. Cyclopamine

    Catalog No. A10249
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    Hedgehog signaling 抑制剂
    Cyclopamine是一种特异性的Hedgehog (Hh)信号通路拮抗剂,作用于Smoothened (Smo),IC50为46 nM。Cyclopamine 抑制Hedgehog信号通路, IC50 为46 nM。 了解更多
  4. TAK-441

    Catalog No. A11351
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    Hedgehog 抑制剂
    TAK-441是吡咯并[3,2-c]吡啶衍生物,作为高效口服活性hedgehog信号抑制剂。 了解更多
  5. SANT-1

    Catalog No. A13095
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    Sonic hedgehog 抑制剂
    SANT-1是有效的细胞渗透性Sonic刺猬(Shh)信号传导抑制剂;平滑活性的高亲和力拮抗剂(KD = 1.2 nM)。以20 nM的IC50抑制平滑的激动剂作用(在Shh-LIGHT2细胞中)。 了解更多
  6. Hh-Ag1.5

    Catalog No. A12920
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    Hedgehog 抑制剂
    Hh-Ag1.5是Hedgehog途径中最有效,选择性最强的小分子激动剂之一,靶向EC50?1 nM的平滑(Smo)。 了解更多
  7. JK 184

    Catalog No. A12925
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    Hedgehog 抑制剂
    JK 184是有效的下游hedgehog (Hh)信号抑制剂,可防止Gli依赖性转录活性(IC50 = 30 nM)。 了解更多
  8. MK-4101

    Catalog No. A16111
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    Hedgehog 抑制剂
    MK-4101是Hedgehog通路的有效和选择性抑制剂。 了解更多
  9. RU-SKI 43

    Catalog No. A16229
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    Hhat 抑制剂
    RU-SKI 43是Hhat(刺猬酰基转移酶)的小分子抑制剂,该酶负责将棕榈酸酯附着到Shh上。 了解更多
  10. HPI-4

    Catalog No. A16349
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    hedgehog 抑制剂
    HPI-4是一种刺猬(Hh)信号通路抑制剂,中位抑制浓度(IC50)小于10μM。 了解更多

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