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HS-10296 hydrochloride is an orally available and third-Generation inhibitor of epidermal growth factor receptor (EGFR)-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.79 mL | 88.95 mL | 177.9 mL |
| 0.5 mM | 3.56 mL | 17.79 mL | 35.58 mL |
| 1 mM | 1.78 mL | 8.9 mL | 17.79 mL |
| 5 mM | 0.36 mL | 1.78 mL | 3.56 mL |
*The above data is based on the productmolecular weight 562.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21661 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 562.11 |
| Formula | C30H36ClN7O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2134096-03-8 |
| Synonyms | HS10296, HS 10296 |
| SMILES | COC(C=C(N(C)CCN(C)C)C(NC(C=C)=O)=C1)=C1NC2=NC(C3=CN(C4CC4)C5=C3C=CC=C5)=CC=N2.[H]Cl |
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