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ICA-121431是人NaV1.3和NaV1.1通道的有效和选择性抑制剂（IC50值分别为13和23 nM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.24 mL | 111.22 mL | 222.44 mL |
| 0.5 mM | 4.45 mL | 22.24 mL | 44.49 mL |
| 1 mM | 2.22 mL | 11.12 mL | 22.24 mL |
| 5 mM | 0.44 mL | 2.22 mL | 4.45 mL |
*The above data is based on the productmolecular weight 449.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13773 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 449.55 |
| Formula | C23H19N3O3S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 313254-51-2 |
| Synonyms | ICA 121431, ICA121431 |
| SMILES | C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)S(=O)(=O)NC4=NC=CS4 |
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