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Icotinib hydrochloride是一种有效的特异性表皮生长因子受体（EGFR）酪氨酸激酶抑制剂（TKI），IC（50）为5 nM，包括EGFR（L858R），EGFR（L861Q），EGFR（T790M）和EGFR的突变体（T790M，L858R）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.37 mL | 116.86 mL | 233.71 mL |
| 0.5 mM | 4.67 mL | 23.37 mL | 46.74 mL |
| 1 mM | 2.34 mL | 11.69 mL | 23.37 mL |
| 5 mM | 0.47 mL | 2.34 mL | 4.67 mL |
*The above data is based on the productmolecular weight 427.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13718 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 427.88 |
| Formula | C22H22ClN3O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1204313-51-8 |
| Synonyms | BPI-2009H |
| SMILES | C#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4.Cl |
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