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Interleukin-22 Antagonist (E117A) Mouse Recombinant
| 目录号 | AP5309 |
|---|---|
| Applications | IL-22 E117A mutant is capable of full inhibition of STAT3 phosphorylation induced by mouse interleukin 22 in HepG cells. Its affinity toward immobilized mIL-22 receptor a1 extracellular domain (mIL-22 Ra1-ECD) or IL-22 binding protein is similar to the non-mutated mouse interleukin 22. Mouse IL-22 antagonist (E117A) has very low agonistic activity in this bioassay. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | IL-22 Antagonist Mouse is lyophilized from a concentrated (1mg/ml) solution in water containing NaHCO3. |
| Protein biological activity | Adooq's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
| Amino acid sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Pro-Val-Asn. |
| Uniprot ACC# | Q9JJY9 |
| Purity | Greater than 98.0% as determined by:(a) Gel filtration chromatography under non-denaturing conditions.(b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel. |
| Stability | Lyophilized Interleukin-22 Mouse Antagonist although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL22 Antagonist should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles. |
| Source | Escherichia Coli. |
| Synonyms | IL-TIF, TIFa, IL-10-related T-cell-derived-inducible factor, IL-22, ILTIF, IL-D110, zcyto18, MGC79382, MGC79384, TIFIL-23. |
| Transportation method | Shipped at Room temp |
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