微信关注
Total item
Cart Subtotal
￥ 0.00 Immunology & Inflammation
-
Piroxicam (Feldene)
Catalog No. A10736 -
Iguratimod (T 614)
Catalog No. A11464 COX-2 抑制剂Iguratimod (T 614)是一种抗风湿剂，能够有效地抑制COX-2的活性，IC50值为20 μM (7.7 μg/mL)，而对 COX-1 无作用；Iguratimod同时为巨噬细胞移动抑制因子 (MIF) 抑制剂，IC50值为6.81 μM。 了解更多 -
Jaceosidin
Catalog No. A12080 Jaceosidin是一种来源于艾蒿的药理活性黄酮，通过阻断培养的人乳腺上皮细胞中erk-1和-2的磷酸化来抑制佛波酯诱导的cox-2和MMP-9的上调。 了解更多 -
Bromfenac sodium
Catalog No. A13244 -
Acetaminophen
Catalog No. A10030 COX 抑制剂Acetaminophen (paracetamol) 是选择性环氧合酶-2 (COX-2) 的抑制剂，IC50 值为 25.8 μM。Acetaminophen 是一种有效的肝 N-乙酰转移酶 2 (NAT2) 抑制剂。它是广泛使用的解热和止痛药。 了解更多 -
Naproxen sodium
Catalog No. A10623 COX 抑制剂Naproxen sodium是一种非选择性的环氧合酶（COX）抑制剂，具有抗炎，解热和镇痛作用。对秋水仙碱引起的认知障碍和氧化应激具有神经保护作用。 了解更多 -
FK 3311
Catalog No. A13332 -
Valdecoxib
Catalog No. A13342 COX-2 抑制剂伐地考昔（Valdecoxib），也称为SC-65872，是一种非甾体类抗炎药（NSAID），用于治疗骨关节炎，类风湿性关节炎以及痛经和月经症状。 它是一种选择性的环氧合酶2（COX-2)抑制剂,IC50为5nM。 了解更多 -
Amfenac Sodium Monohydrate
Catalog No. A16399 COX 抑制剂Amfenac Sodium Monohydrate是一种非甾体止痛消炎药，带有乙酸部分。COX1和COX2的IC50值分别为250 nM和150 nM。 了解更多 -
Carprofen
Catalog No. A16428 -
Timegadine
Catalog No. A17108 COX and lipo-oxygenase 抑制剂Timegadine被发现是一种有效的竞争性环加氧酶（COX）和脂加氧酶抑制剂，IC50的范围从5 nM（洗兔血小板）到20μM（大鼠脑）。在马血小板匀浆的细胞溶质级分和洗涤过的兔血小板中，脂氧化酶的浓度为100μM和100μM。 了解更多 -
Aceclofenac
Catalog No. A17433 COX-2 抑制剂Aceclofenac is a cyclooxygenase-2 inhibitor used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. 了解更多 -
Bromfenac sodium hydrate
Catalog No. A18194 COX-2 抑制剂Bromfenac Sodium Sesquihydrate is a nonsteroidal anti-inflammatory drug (NSAID), which inhibits cyclooxygenase II (COX-2). 了解更多 -
Metamizole sodium hydrate
Catalog No. A18270 COX 抑制剂Dipyrone, also known as Anador and NSC-73205, is a nonsteroidal anti-inflammatory drug used to treat pain (postoperative, colic, cancer, and migraine). 了解更多 -
Teijin compound 1
Catalog No. A13380 CCR 2 antagonistTeijin compound 1 is a specific CCR 2 antagonist with IC50s of 24 and 180 nM in chemotaxis and binding assay, respectively. 了解更多 -
GSK2239633A
Catalog No. A12175 CCR4 antagonistGSK2239633A is a CC-chemokine receptor 4 (CCR4) antagonist, which inhibits the binding of [125I]-TARC to human CCR4 with a pIC50 of 7.96????0.11. 了解更多 -
PF-4136309
Catalog No. A15127 CCR2 antagonistPF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2. 了解更多 -
RS102895 hydrochloride
Catalog No. A20918 CCR2 antagonistRS102895 hydrochloride is a potent CCR2 antagonist, with an IC50 of 360 nM, and shows no effect on CCR1. 了解更多 -
BX471 hydrochloride
Catalog No. A21886 non-peptide CCR1 antagonistBX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. 了解更多 -
Maraviroc (UK-427857)
Catalog No. A10556 CCR 拮抗剂Maraviroc (UK-427857)是CCR5受体拮抗剂类别的抗逆转录病毒药物，用于治疗HIV感染。 了解更多 -
Vicriviroc Malate
Catalog No. A10971 CCR5 拮抗剂Vicriviroc Malate是CCR5拮抗剂，也是HIV-1进入靶细胞的有效抑制剂，对HIV分离株的平均IC50 = 0.46 nM，IC50 = 1?10 nM（n = 52）。 了解更多 -
INCB8761 (PF-4136309)
Catalog No. A11136 -
INCB 3284 dimesylate
Catalog No. A11104 HCCR2 拮抗剂INCB 3284 dimesylate是一种有效的选择性hCCR2拮抗剂，对单核细胞趋化因子分子与hCCR2的结合和趋化活性表现出强烈的拮抗作用。 了解更多 -
TAK-779
Catalog No. A13846 -
Cenicriviroc
Catalog No. A13643 CCR2/CCR5 抑制剂Cenicriviroc是用于治疗HIV感染的实验性候选药物.Cenicriviroc是CCR2和CCR5受体的抑制剂，可使其充当阻止病毒进入人体细胞的进入抑制剂。 了解更多 -
Vicriviroc maleate
Catalog No. A15276 -
ZK-756326 dihydrochloride
Catalog No. A16363 CCR8 激动剂ZK-756326是有效的，选择性的非肽CCR8趋化因子受体激动剂。ZK 756326抑制了CCR8配体I-309（CCL1）的结合，IC（50）值为1.8μM。 了解更多 -
BMS-813160
Catalog No. A17040 -
Cenicriviroc Mesylate
Catalog No. A17028 CCR2/5 receptors 抑制剂Cenicriviroc(TAK-652,TBR-652)是CCR2和CCR5受体的抑制剂，可使其充当防止病毒进入人细胞的进入抑制剂 了解更多 -
BI-639667
Catalog No. A18747 -
PF-04634817
Catalog No. A18659 CCR2 /CCR5 dual 拮抗剂PF-04634817 is an orally administered CCR2 and CCR5 chemokine receptor antagonist, for the treatment of diabetic nephropathies and diabetic macular oedema. 了解更多
FILTER BY:
购物选项
- 分类
-
- IL Receptor (11)
- COX (64)
- CCR (29)
- Toll-like Receptors (19)
- CXCR (30)
- ROS (6)
- NOS (6)
- Keap1-Nrf2 (9)
- LTR (7)
- MALT (3)
- PD-1/PD-L1 (2)
- NADPH oxidase (6)
- PGE Synthase (4)
- Arginase (5)
- Salt-inducible Kinase (SIK) (4)
- Immunology & Inflammation related (11)
- 作用机制
-
- Inhibitor (抑制剂) (115)
- Agonist (激动剂) (18)
- Antagonist (拮抗剂) (50)
- Activator (激活剂) (6)
- Modulator (调节剂) (3)
- 靶点
ADOOQ 产品质量保证
We promise all products to perform as described.