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￥ 0.00 Immunology & Inflammation
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Y320
Catalog No. A11963 -
MCC950 sodium
Catalog No. A13478 -
Fexofenadine HCl
Catalog No. A11859 COX 抑制剂/histamine H1 receptor 激动剂Fexofenadine Hydrochloride是一种抗组胺药，可抑制Cox-1，Cox-2，并且是组胺H1受体激动剂，IC50为246 nM。 了解更多 -
Tepoxalin
Catalog No. A12879 -
Flufenamic acid
Catalog No. A13333 COX 抑制剂Flufenamic acid是一种非甾体类抗炎药（NSAID）。抑制钙激活的氯离子通道（CaCC）。也增加通过TRPC6通道的电流，并抑制通过TRPC3和TRPC7通道的电流。 了解更多 -
Meclofenamate Sodium
Catalog No. A12520 -
Etoricoxib
Catalog No. A13770 COX-2 抑制剂Etoricoxib特异性结合并抑制环氧合酶2（COX-2），从而抑制花生四烯酸向前列腺素的转化。抑制COX-2可以诱导细胞凋亡并抑制肿瘤细胞的增殖和血管生成。 了解更多 -
Xanthohumol
Catalog No. A15919 -
SC 560
Catalog No. A13023 -
Etodolac (AY-24236)
Catalog No. A10371 COX inhibitorEtodolac (AY-24236) is a non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX (IC50=53.5 nM). 了解更多 -
Eicosatetraynoic acid
Catalog No. A19008 COX/LOX inhibitorEicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively). Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 ?M?? 了解更多 -
Naproxen etemesil
Catalog No. A13052 COX-1 and COX-2 inhibitorNaproxen etemesil is a lipophilic, non-acidic, inactive prodrug of naproxen that is hydrolysed to pharmacologically active Naproxen once absorbed. Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay. 了解更多 -
Diclofenac diethylamine
Catalog No. A16503 COX inhibitorDiclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor. 了解更多 -
Diclofenac
Catalog No. A17814 COX inhibitorDiclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively. 了解更多 -
Etoricoxib D4
Catalog No. A21877 COX-2 inhibitorEtoricoxib D4 (MK-0663 D4) is a deuterium labeled Etoricoxib. Etoricoxib is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood. 了解更多 -
Ibuprofen (Advil)
Catalog No. A10461 COX-1 抑制剂Ibuprofen (Advil)是一种非甾体抗炎药(NSAID)，靶向COX-1，IC50为13 μM。 了解更多 -
Ibuprofen Lysine (NeoProfen)
Catalog No. A10462 -
Asaraldehyde (Asaronaldehyde)
Catalog No. A10090 -
Celecoxib
Catalog No. A10193 -
Pravadoline (WIN 48098)
Catalog No. A10749 COX 抑制剂Pravadoline (WIN 48098)是抗炎和前列腺素合成抑制剂，通过抑制环氧合酶（COX）发挥作用。 了解更多 -
Sulindac (Clinoril)
Catalog No. A10878 -
Flunixin meglumine
Catalog No. A11686 COX 抑制剂Flunixin Meglumin是一种有效的环氧化酶（COX）抑制剂，用作止痛剂，具有抗炎和解热作用。 了解更多 -
Acemetacin (Emflex)
Catalog No. A11692 -
Tolfenamic acid
Catalog No. A11693 COX-2 抑制剂Tolfenamic Acid是一种COX-2抑制剂，IC50为0.2μM。它是非甾体抗炎药（NSAID）的一类。它用于治疗偏头痛的症状。 了解更多 -
Nimesulide
Catalog No. A11694 -
Lornoxicam (Xefo)
Catalog No. A11695 COX 抑制剂Lornoxicam (Xefo)是一种非甾体类COX-1/COX-2抑制剂。它是oxicam类的非甾体类抗炎药（NSAID），具有镇痛（缓解疼痛），抗炎和退烧（退烧）特性。 了解更多 -
Licofelone
Catalog No. A11697 COX/LOX 抑制剂Licofelone是一种COX/LOX双重抑制剂，被认为是治疗骨关节炎的药物。它可能会降低与其他仅抑制COX（环氧合酶）的非甾体类抗炎药有关的胃肠道毒性。利福非酮是第一种同时抑制两者的药物。 了解更多 -
Diclofenac sodium
Catalog No. A10304 COX 抑制剂Diclofenac Sodium是一种非选择性的COX抑制剂，完整细胞中的COX-1和-2的IC50分别为0.5μg/ml和0.5μg/ml，作用于绵羊COX-1和COX-2， IC50分别为60和220 nM，用作非甾体类抗炎药（NSAID）来减轻疼痛和减轻疼痛 肿胀发炎。 了解更多 -
Rofecoxib (Vioxx)
Catalog No. A11918 -
Indomethacin (Indocid, Indocin)
Catalog No. A10474 COX 抑制剂Indomethacin (Indocid, Indocin)是一种非选择性COX1和COX2抑制剂，IC50分别为0.1 μg/mL和5 μg/mL。吲哚美辛(吲哚满，吲哚满)是一种非甾体抗炎药，通常用于减轻发热、疼痛、僵硬和肿胀。 了解更多 -
Phenylbutazone (Butazolidin, Butatron)
Catalog No. A10720 COX 抑制剂Phenylbutazone (Butazolidin,Butatron)是一种具有研究意义的化合物，它是一种抗炎和抗增殖剂。 了解更多 -
Piroxicam (Feldene)
Catalog No. A10736 -
Iguratimod (T 614)
Catalog No. A11464 COX-2 抑制剂Iguratimod (T 614)是一种抗风湿剂，能够有效地抑制COX-2的活性，IC50值为20 μM (7.7 μg/mL)，而对 COX-1 无作用；Iguratimod同时为巨噬细胞移动抑制因子 (MIF) 抑制剂，IC50值为6.81 μM。 了解更多 -
Bromfenac sodium
Catalog No. A13244 -
Acetaminophen
Catalog No. A10030 COX 抑制剂Acetaminophen (paracetamol) 是选择性环氧合酶-2 (COX-2) 的抑制剂，IC50 值为 25.8 μM。Acetaminophen 是一种有效的肝 N-乙酰转移酶 2 (NAT2) 抑制剂。它是广泛使用的解热和止痛药。 了解更多 -
Naproxen sodium
Catalog No. A10623 COX 抑制剂Naproxen sodium是一种非选择性的环氧合酶（COX）抑制剂，具有抗炎，解热和镇痛作用。对秋水仙碱引起的认知障碍和氧化应激具有神经保护作用。 了解更多
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- IL Receptor (6)
- COX (60)
- CCR (4)
- Toll-like Receptors (6)
- CXCR (3)
- ROS (3)
- NOS (5)
- Keap1-Nrf2 (4)
- MALT (3)
- PD-1/PD-L1 (2)
- NADPH oxidase (6)
- PGE Synthase (4)
- Arginase (5)
- Salt-inducible Kinase (SIK) (4)
- Immunology & Inflammation related (2)
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