你的浏览器似乎禁用了 JavaScript。
您必须在浏览器中启用JavaScript才能使用本网站的功能。

微信关注
申请试用装

主页 /
Cytoskeleton /
Integrin

Integrin

Quick View
Cyclo(RGDyK)

Catalog No. A21819
Quick View

添加到收藏
αVβ3 integrin inhibitor

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM. 了解更多

Bulk Inquiry
Quick View
Carotegrast

Catalog No. A21997
添加到收藏
α4 integrin receptor inhibitor

Carotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities. 了解更多

Bulk Inquiry
Quick View
ATN-161 trifluoroacetate salt

Catalog No. A21412
Quick View

添加到收藏
integrin α5β1 antagonist

ATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model. 了解更多

Bulk Inquiry
Quick View
ATN-161

Catalog No. A21307
Quick View

添加到收藏
integrin α5β1 antagonist

ATN-161 is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model. 了解更多

Bulk Inquiry
Quick View
MK-0429

Catalog No. A21173
Quick View

添加到收藏
αvβ3 integrin antagonist

MK-0429 (L-000845704) is an orally active, potent, selective and nonpeptide αvβ3 integrin antagonist with an IC50 of 80 nM. 了解更多

Bulk Inquiry
Quick View
Integrin Antagonists 27

Catalog No. A20895
Quick View

添加到收藏
integrin αvβ3 antagonist

Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as s novel anticancer agent. 了解更多

Bulk Inquiry
Quick View
GLPG0187

Catalog No. A13423
Quick View

添加到收藏
Integrin receptor antagonist

GLPG0187 is a broad spectrum integrin receptor antagonist with antitumor activity; inhibits αvβ1-integrin with an IC50 of 1.3 nM. 了解更多

Bulk Inquiry
Quick View
R-BC154

Catalog No. A17184
Quick View

添加到收藏
α4β1/α9β1 抑制剂

R-BC154是高亲和力的荧光α4β1/α9 9β1抑制剂。了解更多

Bulk Inquiry
Quick View
Obtustatin

Catalog No. A17185
Quick View

添加到收藏
α1β1 抑制剂

Obtustatin是高度有效的整联蛋白α1β1抑制剂（α1β1与IV型胶原的结合的IC 50 = 0.8 nM）。与α2β1，βIIbβ3，αvβ3，α4β1，β5β6，α9β1和α4β7相比，α1β1具有选择性。在鸡绒膜尿囊炎模型中抑制FGF2刺激的血管生成。在Lewis肺癌的协同小鼠模型中显示抗肿瘤功效；阻止人黑素瘤在裸鼠中的生长。了解更多

Bulk Inquiry
Quick View
TCS2314

Catalog No. A17193
Quick View

添加到收藏
Integrin 抑制剂

TCS2314是整联蛋白极晚期抗原4（VLA-4，α4β1）拮抗剂，IC50值为4.4 nM。了解更多

Bulk Inquiry
Quick View
BTT-3033

Catalog No. A17200
Quick View

添加到收藏
α2β1 integrin 抑制剂

BTT-3033是α2β1整联蛋白抑制剂。了解更多

Bulk Inquiry
Quick View
BOP sodium salt

Catalog No. A17201
Quick View

添加到收藏
α9β1/α4β1 integrin 抑制剂

BOP sodium salt是新型的双重alpha9beta1/alpha4beta1整联蛋白抑制剂。了解更多

Bulk Inquiry
Quick View
BIO-1211

Catalog No. A17210
Quick View

添加到收藏
Integrin alpha4beta1 抑制剂

BIO-1211是整联蛋白alpha4beta1抑制剂。了解更多

Bulk Inquiry
Quick View
- 最新产品
TR-14035

Catalog No. A17118
Quick View

添加到收藏
Integrin 拮抗剂

TR-14035是α4β7和α4β1整联蛋白的双重拮抗剂。了解更多

Bulk Inquiry
Quick View
A-205804

Catalog No. A13047
Quick View

添加到收藏
Integrin 抑制剂

A-205804是E-选择素和ICAM-1的有效和选择性抑制剂，IC50值分别为20 nM和25 nM。了解更多

Bulk Inquiry
Quick View
CWHM12

Catalog No. A15967
Quick View

添加到收藏
αV integrins 抑制剂

CWHM 12可以抑制所有5个alpha V整联蛋白。CWHM12不仅以与遗传删除方法相同的方式预防纤维化，还可以防止肝和肺中现有纤维化的进展，并逆转了由纤维化对这些器官造成的某些损害。了解更多

Bulk Inquiry
Quick View
Cyclo (RGDyK) trifluoroacetate

Catalog No. A15918
Quick View

添加到收藏
Integrin 抑制剂

Cyclo (RGDyK) trifluoroacetate是一种有效的选择性αVbeta3整联蛋白抑制剂，IC50为20 nM。了解更多

Bulk Inquiry
Quick View
E7820

Catalog No. A15456
Quick View

添加到收藏
lpha-2-integrin 抑制剂

E7820是一种小分子芳香族磺酰胺衍生物，具有潜在的抗血管生成和抗肿瘤活性。E7820通过抑制整合素α2（一种在内皮细胞上表达的细胞粘附分子）来抑制血管生成。了解更多

Bulk Inquiry
Quick View
RGD (Arg-Gly-Asp) Peptides

Catalog No. A15538
Quick View

添加到收藏
Inhibits integrin binding to RGD motifs

RGD (Arg-Gly-Asp) Peptides是一种细胞粘附基序，可以模拟细胞粘附蛋白并与整联蛋白结合。了解更多

Product Citations (1)

Bulk Inquiry
- Kan Zhang, .et al. Integrin-dependent microgliosis mediates ketamine-induced neuronal apoptosis during postnatal rat retinal development, Exp Neurol, 2021, Feb 26;340:113659 PMID: 33640375
Quick View
Cyclo (-RGDfK)

Catalog No. A14923
Quick View

添加到收藏
αvβ3 integrin 抑制剂

Cyclo (-RGDfK)是一种有效的、选择性的整合素抑制剂。了解更多

Product Citations (1)

Bulk Inquiry
- Julian Tu, .et al. A Stable Precursor for Bioorthogonally Removable 3-Isocyanopropyloxycarbonyl (ICPrc) Protecting Groups, Synlett, 2020, 31, A-F
Quick View
Leukadherin 1

Catalog No. A13968
Quick View

添加到收藏
Integrin 激动剂

Leukadherin 1是CD11b/CD18的变构激活剂。增加CD11b/CD18依赖性细胞对血纤蛋白原的粘附（EC50 = 4μM）。了解更多

Bulk Inquiry
Quick View
Pyrintegrin

Catalog No. A12876
Quick View

添加到收藏
pyintegrin是一种细胞可渗透的小分子，可将人类胚胎干细胞（hESC）的存活率提高30倍以上。了解更多

Bulk Inquiry
Quick View
Firategrast (SB 683699)

Catalog No. A12787
Quick View

添加到收藏
α4β1/α4β7 integrin 拮抗剂

Firategrast (SB 683699)是一种口服可生物利用的alpha4 beta1/alpha4 beta7整联蛋白拮抗剂，旨在减少淋巴细胞向中枢神经系统（CNS）的运输。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Higuchi S, .et al. Inhibition of the integrin signal constitutes a mouse iPS cell niche, Dev Growth Differ, 2016, Sep;58(7):586-99 PMID: 27633818
Quick View
Cilengitide trifluoroacetate

Catalog No. A12371
Quick View

添加到收藏
Integrin 抑制剂

Cilengitide trifluoroacetate是一种具有潜在抗肿瘤活性的环状精氨酸-甘氨酸-天冬氨酸肽。西仑吉肽结合并抑制α(v)β(3)和α(v)β(5)整联蛋白的活性，从而抑制内皮细胞-细胞相互作用、内皮细胞-基质相互作用和血管生成。了解更多

Product Citations (1)

Bulk Inquiry
- Yi Han Tan, .et al. Complement-activated vitronectin enhances the invasion of nonphagocytic cells by bacterial pathogens Burkholderia and Klebsiella, Cell Microbiol, 2017, Aug;19(8) PMID: 28186697
Quick View
Cilengitide

Catalog No. A12372
Quick View

添加到收藏
Integrin 抑制剂

Cilengitide是一种具有潜在抗肿瘤活性的环状精氨酸-甘氨酸-天冬氨酸肽。西仑吉肽结合并抑制α(v)β(3)和α(v)β(5)整联蛋白的活性，从而抑制内皮细胞-细胞相互作用、内皮细胞-基质相互作用和血管生成。了解更多

Product Citations (6)

Bulk Inquiry Free Sample
- Marion Bouvet, .et al. Anti-integrin αv therapy improves cardiac fibrosis after myocardial infarction by blunting cardiac PW1+ stromal cells, Sci Rep, 2020, 10: 11404 PMID: 32647159
- Rosalie Richards, .et al. 4D imaging and analysis of multicellular tumour spheroid cell migration and invasion, bioRxiv, 2018, 15 Oct 2018
- Hiroki Kanazawa, .et al. Canstatin inhibits hypoxia-induced apoptosis through activation of integrin/focal adhesion kinase/Akt signaling pathway in H9c2 cardiomyoblasts, PLoS One, 2017, 12(2): e0173051 PMID: 28235037
- Yasuda J, .et al. T3 peptide, a fragment of tumstatin, stimulates proliferation and migration of cardiac fibroblasts through activation of Akt signaling pathway, Naunyn Schmiedebergs Arch Pharmacol, 2017, Nov;390(11):1135-1144 PMID: 28785775
- Yasuda J, .et al. T3 peptide, an active fragment of tumstatin, inhibits H2O2-induced apoptosis in H9c2 cardiomyoblasts, Eur J Pharmacol, 2017, Jul 15;807:64-70 PMID: 28457922
- Hsian-Yu Wang, .et al. Non-small-cell lung cancer cells combat epidermal growth factor receptor tyrosine kinase inhibition through immediate adhesion-related responses, Onco Targets Ther, 2016, 9: 2961-2973 PMID: 27284246
Quick View
Zaurategrast (CDP323)

Catalog No. A11614
Quick View

添加到收藏
VCAM-1 拮抗剂

Zaurategrast (CDP323)是与α4-整合素结合的血管细胞粘附分子1的小分子前药拮抗剂。了解更多

Product Citations (1)

Bulk Inquiry
- Mustafa Ahmadzai, .et al. Integrins are Mechanosensors That Modulate Human Eosinophil Activation, Front Immunol, 2015, 6: 525 PMID: 26539194

溶液配制计算器

分子量计算器

稀释计算器

摩尔浓度计算器

ADOOQ 产品质量保证

Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.