IPI-3063

Name: IPI-3063
SKU: A16800

目录号: A16800

selective p110δ 抑制剂

IPI-3063 Chemical Structure

CAS NO. 1425043-73-7

IPI-3063是一种有效的选择性p110δ抑制剂，生化IC50为2.5±1.2 nM，其他I类PI3K亚型（p110α，p110β，p110γ）的IC50值至少高400倍。

库存：现货

规格	价格	数量
2 mg	￥ 700.00
5 mg	￥ 1,400.00
25 mg	￥ 2,450.00

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生物活性

IPI-3063是一种有效的选择性p110δ抑制剂，生化IC50为2.5±1.2 nM，其他I类PI3K亚型（p110α，p110β，p110γ）的IC50值至少高400倍。

溶解度 *

In vitro	DMSO	83 mg/mL (182.21 mM)
	Water	Insoluble
	Ethanol	11 mg/mL (24.15 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.95 mL	109.77 mL	219.53 mL
0.5 mM	4.39 mL	21.95 mL	43.91 mL
1 mM	2.2 mL	10.98 mL	21.95 mL
5 mM	0.44 mL	2.2 mL	4.39 mL

*The above data is based on the productmolecular weight 455.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16800
作用机制	Inhibitor (抑制剂)
M. Wt	455.51
Formula	C25H25N7O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1425043-73-7
Synonyms	IPI3063, IPI 3063
SMILES	O=C1N(C)C=C(C2=CC=CC(C=C([C@@H](NC3=C(C#N)C(N)=NC=N3)C)N4C(C)C)=C2C4=O)C=C1