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￥ 0.00 Isocitrate Dehydrogenase (IDH)
14 个项目
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Mutant IDH1 inhibitor
Catalog No. A21150 mutant IDH1 R132H inhibitorMutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of < 72 nM. 了解更多 -
Mutant IDH1-IN-2
Catalog No. A21339 IDH inhibitorMutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in Fluorescence biochemical assay. 了解更多 -
Mutant IDH1-IN-1
Catalog No. A21359 mutant-selective IDH1 inhibitorMutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively. 了解更多 -
AGI-5198 (IDH-C35)
Catalog No. A12902 -
AG-120 (Ivosidenib)
Catalog No. A14386 -
Vorasidenib
Catalog No. A16908 IDH1 抑制剂Vorasidenib (AG-881)是一种有效且选择性的口服抑制剂，可抑制细胞质中异柠檬酸脱氢酶1型(IDH1，IDH1 [NADP+]可溶)和2型（IDH2异柠檬酸脱氢酶[NADP+]）的突变形式。线粒体中的线粒体，具有潜在的抗肿瘤活性。 了解更多 -
BAY-1436032
Catalog No. A17059 -
Olutasidenib (FT-2102)
Catalog No. A18789 IDH1 inhibitorOlutasidenib is a potent, selective inhibitor of mutant Isocitrate dehydrogenase (IDH)1 for the treatment of acute myeloid leukemia. 了解更多 -
Mutant IDH1-IN-4
Catalog No. A19106 IDH1 inhibitorMutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ?? 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells. 了解更多 -
IDH1 Inhibitor 2
Catalog No. A18420 IDH1 inhibitorDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM. 了解更多
14 个项目
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