Itraconazole (Sporanox)

Name: Itraconazole (Sporanox)
SKU: A10489

目录号: A10489

Product Citations (1)

Itraconazole (Sporanox) Chemical Structure

CAS NO. 84625-61-6

Itraconazole (Sporanox)是CYP3A4相对有效的抑制剂，IC50为6.1nM，用作三唑类抗真菌剂。

库存：现货

规格	价格	数量
100 mg	￥ 385.00
250 mg	￥ 840.00
500 mg	￥ 1,400.00
1000 mg	￥ 2,450.00

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生物活性

Itraconazole (Sporanox)是CYP3A4相对有效的抑制剂，IC50为6.1nM，用作三唑类抗真菌剂。

靶点信息

CYP3A4

溶解度 *

In vitro (25°C)	DMSO	Warmed: 7 mg/mL (9.91 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+40% PEG 300+10% Tween 80+45% ddH2O	1.66 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.17 mL	70.86 mL	141.71 mL
0.5 mM	2.83 mL	14.17 mL	28.34 mL
1 mM	1.42 mL	7.09 mL	14.17 mL
5 mM	0.28 mL	1.42 mL	2.83 mL

*The above data is based on the productmolecular weight 705.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10489
M. Wt	705.65
Formula	C35H38Cl2N8O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	84625-61-6
Synonyms	Sporanox
SMILES	CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OC[C@H]5CO[C@](O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl