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JAK3-IN-1 is a potent JAK3 inhibitor with IC50 of 4.8 nM, also inhibits JAK1 (IC50 = 896 nM) and JAK2 (IC50 = 1050 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.68 mL | 98.42 mL | 196.84 mL |
| 0.5 mM | 3.94 mL | 19.68 mL | 39.37 mL |
| 1 mM | 1.97 mL | 9.84 mL | 19.68 mL |
| 5 mM | 0.39 mL | 1.97 mL | 3.94 mL |
*The above data is based on the productmolecular weight 508.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20734 |
|---|---|
| M. Wt | 508.02 |
| Formula | C26H30ClN7O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1805787-93-2 |
| Synonyms | JAK3IN1; JAK3 IN 1; JAK3IN-1; JAK3-IN1 |
| SMILES | O=C(C=C)NC1=CC(CNC2=NC(NC3=C(OC)C=C(N4CCN(C)CC4)C=C3)=NC=C2Cl)=CC=C1 |
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