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JBSNF-000088 (6-Methoxynicotinamide), a analog of nicotinamide (NA), is a potent Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 1.8 ?M, 2.8 ?M, and 5.0??M for human NNMT, monkey NNMT and mouse NNMT, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 65.72 mL | 328.62 mL | 657.25 mL |
| 0.5 mM | 13.14 mL | 65.72 mL | 131.45 mL |
| 1 mM | 6.57 mL | 32.86 mL | 65.72 mL |
| 5 mM | 1.31 mL | 6.57 mL | 13.14 mL |
*The above data is based on the productmolecular weight 152.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22190 |
|---|---|
| M. Wt | 152.15 |
| Formula | C7H8N2O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 7150-23-4 |
| Synonyms | 6-Methoxynicotinamide |
| SMILES | O=C(N)C1=CC=C(OC)N=C1 |
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