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JNK-IN-7是一种相对选择性的JNKs抑制剂(对于JNK1/2/3,IC50 = 1.54/1.99/0.75 nM);也绑定到IRAK1,PIK3C3,PIP5K3和PIP4K2C。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.26 mL | 101.3 mL | 202.61 mL |
0.5 mM | 4.05 mL | 20.26 mL | 40.52 mL |
1 mM | 2.03 mL | 10.13 mL | 20.26 mL |
5 mM | 0.41 mL | 2.03 mL | 4.05 mL |
*The above data is based on the productmolecular weight 493.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A15136 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 493.56 |
Formula | C28H27N7O2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1408064-71-0 |
Synonyms | JNK inhibitor |
SMILES | CN(C)CC=CC(=O)NC1=CC=CC(=C1)C(=O)NC2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CN=CC=C4 |
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