Keap1-Nrf2

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  1. Oltipraz

    Catalog No. A13164
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    Nrf2 activator
    Oltipraz抑制HIF-1alpha活性和HIF-1alpha依赖性肿瘤生长,这可能是由于S6K1抑制结合H2O2清除作用导致HIF-1alpha稳定性降低所致。 了解更多
  2. CDDO-EA

    Catalog No. A16299
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    Nrf2 activator
    CDDO-EA是Nrf2/ARE的激活剂;神经保护作用。 了解更多
  3. NK-252

    Catalog No. A16300
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    Nrf2 activator
    NK-252是Nrf2活化剂,与OPZ相比,具有更大的Nrf2活化电位。 了解更多
  4. AKBA

    Catalog No. A17908
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    Nrf2 activator
    AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. 了解更多
  5. Nrf2-IN-1

    Catalog No. A12561
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    Nrf2 inhibitor
    Nrf2-IN-1 (Compound 4f) is an inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2), acts as a promising agent in acute myeloid leukemia (AML) therapy. 了解更多
  6. (R)-Sulforaphane

    Catalog No. A21690
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    Keap1/Nrf2/ARE pathway inducer
    (R)-Sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway. (R)-Sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. 了解更多
  7. RTA-408

    Catalog No. A14417
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    Nrf2 抑制剂
    RTA-408是一种合成的三萜类化合物,可有效激活抗氧化转录因子Nrf2并抑制促炎转录因子NF-kB。 了解更多
  8. Brusatol

    Catalog No. A16893
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    Nrf2 抑制剂
    Brusatol是一种生化物质,从Brucea javanica植物中分离出来,可抑制Nrf2。 了解更多
  9. ML-385

    Catalog No. A17172
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    NRF2 抑制剂
    ML-385是核因子红系2相关因子2(Nrf2)的抑制剂,IC50值为1.9μM。 了解更多

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