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KN-62是一种有效，选择性的钙调蛋白依赖性蛋白激酶 II (CaMK-II)抑制剂。
靶点信息
| CaMKII | ||||
| 0.9 μM(Ki) |
| In vitro | DMSO | 96 mg/mL (132.99 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.85 mL | 69.27 mL | 138.54 mL |
| 0.5 mM | 2.77 mL | 13.85 mL | 27.71 mL |
| 1 mM | 1.39 mL | 6.93 mL | 13.85 mL |
| 5 mM | 0.28 mL | 1.39 mL | 2.77 mL |
*The above data is based on the productmolecular weight 721.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11473 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 721.8 |
| Formula | C38H35N5O6S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 127191-97-3 |
| SMILES | CN([C@@H](CC1=CC=C(C=C1)OS(=O)(=O)C2=CC=CC3=C2C=CN=C3)C(=O)N4CCN(CC4)C5=CC=CC=C5)S(=O)(=O)C6=CC=CC7=C6C=CN=C7 |
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