KPT 335

目录号: A16078

SINE 抑制剂

KPT 335

KPT 335 Chemical Structure

CAS NO. 1392136-43-4

KPT 335是口服可生物利用的核出口选择性抑制剂(SINE)。

库存: 现货

规格 价格 数量
5 mg
¥ 840.00
10 mg
¥ 1,260.00
50 mg
¥ 5,460.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

KPT 335是口服可生物利用的核出口选择性抑制剂(SINE)。
靶点信息
CRM1
In vitro (25°C) DMSO 83 mg/mL (187.65 mM)
Water Insoluble
Ethanol Warmed: 10 mg/mL
In vivo 5% DMSO+corn oil 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.61 mL 113.04 mL 226.08 mL
0.5 mM 4.52 mL 22.61 mL 45.22 mL
1 mM 2.26 mL 11.3 mL 22.61 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16078
作用机制 Inhibitor (抑制剂)
M. Wt 442.32
Formula C18H12F6N6O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1392136-43-4
Synonyms Verdinexor
SMILES O=C(NNC1=NC=CC=C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2

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