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KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.04 mL | 100.22 mL | 200.44 mL |
| 0.5 mM | 4.01 mL | 20.04 mL | 40.09 mL |
| 1 mM | 2 mL | 10.02 mL | 20.04 mL |
| 5 mM | 0.4 mL | 2 mL | 4.01 mL |
*The above data is based on the productmolecular weight 498.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18447 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 498.91 |
| Formula | C25H21ClF2N4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2349393-21-9 |
| SMILES | FC1=CC=CC(O)=C1C2=C(F)C(N=CC(N3C)=C4N5[C@H](CN(C(C=C)=O)[C@H](C)C5)C3=O)=C4C=C2Cl |
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