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L-778123 hydrochloride是FPTase和GGPTase-I双重抑制剂,在酶抑制测定中IC50为2 nM和98 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.61 mL | 113.04 mL | 226.07 mL |
| 0.5 mM | 4.52 mL | 22.61 mL | 45.21 mL |
| 1 mM | 2.26 mL | 11.3 mL | 22.61 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.52 mL |
*The above data is based on the productmolecular weight 442.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15796 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 442.34 |
| Formula | C22H21Cl2N5O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 253863-00-2 |
| Synonyms | L778123 HCl, L 778123 HCl |
| SMILES | C1CN(C(=O)CN1CC2=CN=CN2CC3=CC=C(C=C3)C#N)C4=CC(=CC=C4)Cl.Cl |
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