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Laninamivir (CS-8958)是一种神经氨酸酶抑制剂，正在研究用于治疗和预防A型流感病毒和B型流感病毒。其对流感病毒 H12N5 NA (N5)，pH1N1 N1 NA (p09N1) 和 A/RI/5+/1957 H2N2 N2 (p57N2) 的 IC50 分别为 0.90 nM、1.83 nM 和 3.12 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.62 mL | 143.12 mL | 286.25 mL |
| 0.5 mM | 5.72 mL | 28.62 mL | 57.25 mL |
| 1 mM | 2.86 mL | 14.31 mL | 28.62 mL |
| 5 mM | 0.57 mL | 2.86 mL | 5.72 mL |
*The above data is based on the productmolecular weight 349.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12998 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 349.35 |
| Formula | C13H19D3N4O7 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 203120-17-6 |
| Synonyms | CS-8958, CS8958 |
| SMILES | CC(=O)NC1C(C=C(OC1C(C(CO)O)OC)C(=O)O)N=C(N)N |
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