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LAQ824 (NVP-LAQ824, Dacinostat)

LAQ824 (NVP-LAQ824, Dacinostat)

Name: LAQ824 (NVP-LAQ824, Dacinostat)
SKU: A10516

目录号: A10516

HDAC 抑制剂

Product Citations (1)

LAQ824 (NVP-LAQ824, Dacinostat) Chemical Structure

CAS NO. 404951-53-7

LAQ824 (NVP-LAQ824)是一种有效的新型组蛋白去乙酰化酶抑制剂，具有显著的抗多发性骨髓瘤活性。

库存：现货

规格	价格	数量
10 mg	￥ 910.00
50 mg	￥ 3,360.00
100 mg	￥ 5,600.00
10mM * 1mL in DMSO	￥ 756.00

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生物活性

LAQ824 (NVP-LAQ824)是一种有效的新型组蛋白去乙酰化酶抑制剂，具有显著的抗多发性骨髓瘤活性。

靶点信息

HDAC
32 nM

溶解度 *

In vitro (25°C)	DMSO	66 mg/mL (173.93 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%DMSO+40%PEG300+5%Tween80+50%ddH2O	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.35 mL	131.75 mL	263.5 mL
0.5 mM	5.27 mL	26.35 mL	52.7 mL
1 mM	2.64 mL	13.18 mL	26.35 mL
5 mM	0.53 mL	2.64 mL	5.27 mL

*The above data is based on the productmolecular weight 379.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10516
作用机制	Inhibitor (抑制剂)
M. Wt	379.5
Formula	C22H25N3O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	404951-53-7
Synonyms	NVP-LAQ824, Dacinostat, LAQ-824
SMILES	C1=CC=C2C(=C1)C(=CN2)CCN(CCO)CC3=CC=C(C=C3)/C=C/C(=O)NO