微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
Lazertinib (YH25448,GNS-1480)是一种有效的，高度突变选择性和不可逆的EGFR-TKI，对于Del19/T790M，L858R/T790M，Del19，Del19，IC50值分别为1.7 nM，2 nM，5 nM，20.6 nM和76 nM。L85R和野生型EGFR分别显示出更高的IC50值，即抗药性ErbB2和ErbB4。
| In vitro | DMSO | 4 mg/mL (7.21 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.03 mL | 90.15 mL | 180.29 mL |
| 0.5 mM | 3.61 mL | 18.03 mL | 36.06 mL |
| 1 mM | 1.8 mL | 9.01 mL | 18.03 mL |
| 5 mM | 0.36 mL | 1.8 mL | 3.61 mL |
*The above data is based on the productmolecular weight 554.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16827 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 554.66 |
| Formula | C30H34N8O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1903008-80-9 |
| Synonyms | YH 25448, YH-25448, GNS1480, GNS 1480 |
| SMILES | C=CC(NC1=CC(NC2=NC=CC(N3N=C(C4=CC=CC=C4)C(CN(C)C)=C3)=N2)=C(OC)C=C1N5CCOCC5)=O |
产品资料
产品标签
Product Questions
Product Questions
No Questions
Keywords:购买 Lazertinib (YH25448,GNS-1480) | Lazertinib (YH25448,GNS-1480) 供应商 | 订购 Lazertinib (YH25448,GNS-1480) | Lazertinib (YH25448,GNS-1480) 价格 | Lazertinib (YH25448,GNS-1480) 生产商 | 订单 Lazertinib (YH25448,GNS-1480) | Lazertinib (YH25448,GNS-1480) 代理商 | 购买 1903008-80-9| 1903008-80-9 供应商 | 订购 1903008-80-9 | 1903008-80-9 价格 | 1903008-80-9 生产商 | 订单 1903008-80-9 | 1903008-80-9 代理商|buy Lazertinib (YH25448,GNS-1480) | Lazertinib (YH25448,GNS-1480) Supplier | purchase Lazertinib (YH25448,GNS-1480) | Lazertinib (YH25448,GNS-1480) cost | Lazertinib (YH25448,GNS-1480) manufacturer | order Lazertinib (YH25448,GNS-1480) | Lazertinib (YH25448,GNS-1480) distributor | buy 1903008-80-9| 1903008-80-9 Supplier | purchase 1903008-80-9 | 1903008-80-9 cost | 1903008-80-9 manufacturer | order 1903008-80-9 | 1903008-80-9 distributor