LCZ696 (Valsartan)

Name: LCZ696 (Valsartan)
SKU: A14206

目录号: A14206

angiotensin receptor-neprilysin 抑制剂

LCZ696 (Valsartan) Chemical Structure

CAS NO. 936623-90-4

LCZ696 (Valsartan)是一种生物利用型双效血管紧张素受体-中性溶血素抑制剂（ARNi），用于治疗高血压和心力衰竭。

库存：现货

规格	价格	数量
5 mg	￥ 455.00
10 mg	￥ 630.00
25 mg	￥ 1,260.00
10mM * 1mL in DMSO	￥ 700.00

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产品详情

生物活性

LCZ696 (Valsartan)是一种生物利用型双效血管紧张素受体-中性溶血素抑制剂（ARNi），用于治疗高血压和心力衰竭。

靶点信息

RAAS

溶解度 *

In vitro	DMSO	Warmed: 26 mg/mL (28.38 mM)
	Water	Warmed: 88 mg/mL (96.07 mM)
	Ethanol	Warmed: 8 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10.92 mL	54.59 mL	109.17 mL
0.5 mM	2.18 mL	10.92 mL	21.83 mL
1 mM	1.09 mL	5.46 mL	10.92 mL
5 mM	0.22 mL	1.09 mL	2.18 mL

*The above data is based on the productmolecular weight 915.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14206
作用机制	Inhibitor (抑制剂)
M. Wt	915.98
Formula	C24H29N5O3.C24H29NO5.5/2H2O.3Na
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	936623-90-4
Synonyms	LCZ 696, LCZ-696
SMILES	CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O.CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O.O.O.O.[Na+].[Na+].[Na+]