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LDN-192960 hydrochloride is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.92 mL | 124.58 mL | 249.16 mL |
| 0.5 mM | 4.98 mL | 24.92 mL | 49.83 mL |
| 1 mM | 2.49 mL | 12.46 mL | 24.92 mL |
| 5 mM | 0.5 mL | 2.49 mL | 4.98 mL |
*The above data is based on the productmolecular weight 401.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21390 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 401.35 |
| Formula | C18H22Cl2N2O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2309172-48-1 |
| Synonyms | LDN 192960, LDN192960 |
| SMILES | NCCCSC1=C(C=C(OC)C=C2)C2=NC3=CC=C(OC)C=C31.Cl.Cl |
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