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Lerociclib dihydrochloride

Lerociclib dihydrochloride

Name: Lerociclib dihydrochloride
SKU: A21577

目录号: A21577

CDK4/CDK6 inhibitor

Lerociclib dihydrochloride Chemical Structure

CAS NO. 2097938-59-3

Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 1 nM and 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.

库存：现货

规格	价格	数量
5 mg	￥ 3,465.00
10 mg	￥ 5,971.00
50 mg	￥ 17,710.00
100 mg	￥ 35,420.00

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生物活性

Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 1 nM and 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.26 mL	91.32 mL	182.64 mL
0.5 mM	3.65 mL	18.26 mL	36.53 mL
1 mM	1.83 mL	9.13 mL	18.26 mL
5 mM	0.37 mL	1.83 mL	3.65 mL

*The above data is based on the productmolecular weight 547.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21577
作用机制	Inhibitor (抑制剂)
M. Wt	547.52
Formula	C26H36Cl2N8O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2097938-59-3
Synonyms	G1T38 dihydrochloride, G1T 38, G1T-38
SMILES	O=C1NCC2(N3C1=CC4=CN=C(NC5=NC=C(N6CCN(C(C)C)CC6)C=C5)N=C43)CCCCC2.[H]Cl.[H]Cl