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Levosimendan是一种Ca2+敏化剂，通过与cardiac troponin C (cTnC)结合而发挥作用，这种作用具有钙依赖性。
靶点信息
| Cardiac troponin C | ||||
| In vitro (25°C) | DMSO | 48 mg/mL (171.26 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+40%PEG 300+5%Tween80+50%ddH2O | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.68 mL | 178.39 mL | 356.77 mL |
| 0.5 mM | 7.14 mL | 35.68 mL | 71.35 mL |
| 1 mM | 3.57 mL | 17.84 mL | 35.68 mL |
| 5 mM | 0.71 mL | 3.57 mL | 7.14 mL |
*The above data is based on the productmolecular weight 280.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11874 |
|---|---|
| M. Wt | 280.29 |
| Formula | C14H12N6O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 141505-33-1 |
| SMILES | C[C@@H]1CC(=O)NN=C1C2=CC=C(C=C2)NN=C(C#N)C#N |
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