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Liarozole dihydrochloride (R75251; R85246) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.2 mL | 131 mL | 261.99 mL |
| 0.5 mM | 5.24 mL | 26.2 mL | 52.4 mL |
| 1 mM | 2.62 mL | 13.1 mL | 26.2 mL |
| 5 mM | 0.52 mL | 2.62 mL | 5.24 mL |
*The above data is based on the productmolecular weight 381.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21853 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 381.69 |
| Formula | C17H15Cl3N4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1883548-96-6 |
| Synonyms | R75251 dihydrochloride, R 75251, R-75251 |
| SMILES | ClC1=CC(C(C2=CC=C3N=CNC3=C2)N4C=CN=C4)=CC=C1.[H]Cl.[H]Cl |
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