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lorcaserin hydrochloride (APD-356)是血清素2C受体激动剂，可指示与减少热量饮食和增加体育锻炼以减轻慢性体重成人管理。
靶点信息
| Human 5-HT2C | Rat 5-HT2C | |||
| 15 nM(Ki) | 29 nM(Ki) |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 43.08 mL | 215.38 mL | 430.76 mL |
| 0.5 mM | 8.62 mL | 43.08 mL | 86.15 mL |
| 1 mM | 4.31 mL | 21.54 mL | 43.08 mL |
| 5 mM | 0.86 mL | 4.31 mL | 8.62 mL |
*The above data is based on the productmolecular weight 232.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12598 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 232.15 |
| Formula | C11H14ClN.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 846589-98-8 |
| Synonyms | APD-356,APD356,APD 356, BELVIQ |
| SMILES | C[C@H]1CNCCC2=C1C=C(C=C2)Cl.Cl |
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