Lovastatin (Mevacor)

Name: Lovastatin (Mevacor)
SKU: A11877

目录号: A11877

HMG-CoA reductase 抑制剂

Lovastatin (Mevacor) Chemical Structure

CAS NO. 75330-75-5

Lovastatin (Mevacor)是HMG-CoA还原酶的抑制剂，IC50为3.4 nM，用于降低胆固醇。

库存：现货

规格	价格	数量
50 mg	￥ 420.00
100 mg	￥ 700.00
250 mg	￥ 1,540.00
500 mg	￥ 2,450.00

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生物活性

Lovastatin (Mevacor)是HMG-CoA还原酶的抑制剂，IC50为3.4 nM，用于降低胆固醇。

靶点信息

HMG-CoA reductase (Cell-free assay)
3.4 nM

溶解度 *

In vitro (25°C)	DMSO	7 mg/mL (17.3 mM)
	Water	Insoluble
	Ethanol	5 mg/mL (12.36 mM)
In vivo	5% DMSO+40%PEG 300+ 5% Tween80 + 50% ddH2O	2.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.72 mL	123.6 mL	247.19 mL
0.5 mM	4.94 mL	24.72 mL	49.44 mL
1 mM	2.47 mL	12.36 mL	24.72 mL
5 mM	0.49 mL	2.47 mL	4.94 mL

*The above data is based on the productmolecular weight 404.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11877
作用机制	Inhibitor (抑制剂)
M. Wt	404.54
Formula	C24H36O5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	75330-75-5
SMILES	CC[C@H](C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C